日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists

一系列α螺旋偏向的超短胰高血糖素样肽-1受体激动剂的设计、构效关系和计算建模研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30010012
Sawyer, Jonathon R; Audie, Joseph A; Swanson, Jon; Diller, David; Santiago, Solimar; Gribkoff, Valentin K; Ackerman, Allison; Hruby, Victor J; Gobbo, Gianpaolo; Bellucci, Michael A; Glauser, William A; Pentelute, Brad L; Sawyer, Tomi K
信号转导
发表日期：2024
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MC4R biased signalling and the conformational basis of biological function selections

MC4R偏向性信号传导和生物功能选择的构象基础

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.17441
Liu, Zekun; Hruby, Victor J
信号转导
发表日期：2022
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Aged Brains Express Less Melanocortin Receptors, Which Correlates with Age-Related Decline of Cognitive Functions

老年人大脑中黑皮质素受体的表达减少，这与认知功能的年龄相关性衰退有关。

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules26206266
Zhou, Yang; Chawla, Monica K; Rios-Monterrosa, Jose L; Wang, Lingzhi; Zempare, Marc A; Hruby, Victor J; Barnes, Carol A; Cai, Minying
信号转导
神经科学
发表日期：2021
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Multiple Applications of a Novel Biarsenical Imaging Probe in Fluorescence and PET Imaging of Melanoma

一种新型双砷成像探针在黑色素瘤荧光成像和PET成像中的多种应用

期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.0c00671
Kondrashov, Mikhail; Svensson, Samuel P S; Ström, Peter; Westermark, Andreas; Jacobson-Ingemyr, Hanna; Takano, Akihiro; Tari, Lenke; Tóth, Miklós; Cai, Minying; Hruby, Victor J; Schou, Magnus
IF
黑色素瘤
发表日期：2021
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Multifunctional Enkephalin Analogs with a New Biological Profile: MOR/DOR Agonism and KOR Antagonism

具有全新生物学特性的多功能脑啡肽类似物：MOR/DOR激动剂和KOR拮抗剂

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines9060625
Lee, Yeon Sun; Remesic, Michael; Ramos-Colon, Cyf; Wu, Zhijun; LaVigne, Justin; Molnar, Gabriella; Tymecka, Dagmara; Misicka, Aleksandra; Streicher, John M; Hruby, Victor J; Porreca, Frank
神经科学
发表日期：2021
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Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

基于向日葵胰蛋白酶抑制剂-1的环肽骨架开发新型黑皮质素受体激动剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.8b00170
Durek Thomas, Cromm Philipp M, White Andrew M, Schroeder Christina I, Kaas Quentin, Weidmann Joachim, Ahmad Fuaad Abdullah, Cheneval Olivier, Harvey Peta J, Daly Norelle L, Zhou Yang, Dellsén Anita, Österlund Torben, Larsson Niklas, Knerr Laurent, Bauer Udo, Kessler Horst, Cai Minying, Hruby Victor J, Plowright Alleyn T, Craik David J
免疫/内分泌
发表日期：2018
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Structural Insights into Selective Ligand-Receptor Interactions Leading to Receptor Inactivation Utilizing Selective Melanocortin 3 Receptor Antagonists

利用选择性黑皮质素3受体拮抗剂揭示导致受体失活的选择性配体-受体相互作用的结构信息

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.7b00407
Cai, Minying; Marelli, Udaya Kiran; Mertz, Blake; Beck, Johannes G; Opperer, Florian; Rechenmacher, Florian; Kessler, Horst; Hruby, Victor J
信号转导
发表日期：2017
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Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain

合成和研究混合型μ-阿片受体和δ-阿片受体激动剂作为治疗疼痛的潜在二价配体

期刊:Journal of Heterocyclic Chemistry
影响因子:2.4
doi:10.1002/jhet.2696
Vardanyan, Ruben S; Cain, James P; Haghighi, Saghar Mowlazadeh; Kumirov, Vlad K; McIntosh, Mary I; Sandweiss, Alexander J; Porreca, Frank; Hruby, Victor J
信号转导
发表日期：2017
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Design of cyclized selective melanotropins

环化选择性促黑素的设计

期刊:Biopolymers
影响因子:3.2
doi:10.1002/bip.22976
Cai, Minying; Hruby, Victor J
发表日期：2016
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Design of cyclic peptides with biological activities from biologically active peptides: the case of peptide modulators of melanocortin receptors

从具有生物活性的肽设计具有生物活性的环状肽：以黑皮质素受体肽调节剂为例

期刊:Biopolymers
影响因子:3.2
doi:10.1002/bip.22929
Hruby, Victor J
信号转导
发表日期：2016
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