日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Platelets as Central Modulators of Post-Cardiac Arrest Syndrome: Mechanisms and Therapeutic Implications

血小板作为心脏骤停后综合征的核心调节因子：机制和治疗意义

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom16010134
Wang, Chen-Hsu; Jan, Jing-Shiun; Yang, Chih-Hao; Hsia, Chih-Wei; Yen, Ting-Lin
血小板
发表日期：2026
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Distinct Thromboxane A₂-Dependent Pathways Regulate Arachidonic Acid-Triggered VASP Phosphorylation at Ser239 and Ser157 in Human Platelets: Real-Time Visualization Reveals Superior Antithrombotic Efficacy by Targeting Thromboxane A₂ Signaling over Cyclooxygenase Inhibition

不同的血栓素A₂依赖性通路调节人血小板中花生四烯酸触发的VASP在Ser239和Ser157位点的磷酸化：实时可视化显示，靶向血栓素A₂信号通路比抑制环氧合酶具有更优的抗血栓疗效

期刊:Journal of Cellular Physiology
影响因子:4
doi:10.1002/jcp.70160
Sheu, Joen-Rong; Huang, Wei-Chieh; Chang, Chao-Chien; Hsia, Chih-Wei; Hsia, Chih-Hsuan; Jayakumar, Thanasekaran; Hou, Shaw-Min
血小板
VASP
信号转导
心血管
Human
磷酸化
发表日期：2026
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Lipopolysaccharide Potentiates Platelet Aggregation in Association with Apoptosis Through a Novel TLR4-Bax/Bcl-2-Mitochondrial Dysfunction Axis in Humans

脂多糖通过新型TLR4-Bax/Bcl-2-线粒体功能障碍轴增强血小板聚集并促进细胞凋亡

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15121638
Chen, Chun-Chao; Hsia, Chih-Wei; Huang, Wei-Chieh; Chang, Chao-Chien; Darmanto, Arief Gunawan; Sheu, Joen-Rong
血小板
Bcl-2
凋亡
表观遗传
Apoptosis
TLR4
Human
线粒体
细胞生物学
发表日期：2025
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Glabridin Suppresses Macrophage Activation by Lipoteichoic Acid In Vitro: The Crucial Role of MAPKs-IL-1β-iNOS Axis Signals in Peritoneal and Alveolar Macrophages.

光甘草定在体外抑制脂磷壁酸对巨噬细胞的活化：MAPKs-IL-1β-iNOS轴信号在腹膜和肺泡巨噬细胞中的关键作用

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom15020174
Hou Shaw-Min, Yang Chun-Ming, Huang Wei-Chieh, Cheng Ssu-Wei, Yen Ting-Lin, Hsia Chih-Wei, Hsieh Cheng-Ying, Hsia Chih-Hsuan
细胞生物学
发表日期：2025
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Eugenol Suppresses Platelet Activation and Mitigates Pulmonary Thromboembolism in Humans and Murine Models

丁香酚抑制血小板活化并减轻人类和小鼠模型中的肺血栓栓塞

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25042098
Huang, Wei-Chieh; Shu, Lan-Hsin; Kuo, Yu-Ju; Lai, Kevin Shu-Leung; Hsia, Chih-Wei; Yen, Ting-Lin; Hsia, Chih-Hsuan; Jayakumar, Thanasekaran; Yang, Chih-Hao; Sheu, Joen-Rong
血小板
Human
心血管
发表日期：2024
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Ginkgetin effectively mitigates collagen and AA-induced platelet activation via PLCγ2 but not cyclic nucleotide-dependent pathway in human

银杏黄素通过PLCγ2途径而非环核苷酸依赖性途径有效减轻胶原蛋白和花生四烯酸诱导的血小板活化。

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.18139
Hsia, Chih-Wei; Shu, Lan-Hsin; Lee, Ai-Wei; Tran, Oanh-Thi; Yang, Chih-Hao; Yen, Ting-Lin; Huang, Wei-Chieh; Hsia, Chih-Hsuan; Jayakumar, Thanasekaran; Chiou, Kuan-Rau; Sheu, Joen-Rong
血小板
发表日期：2024
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Eugenol: A Potential Modulator of Human Platelet Activation and Mouse Mesenteric Vascular Thrombosis via an Innovative cPLA2-NF-κB Signaling Axis

丁香酚：通过创新的cPLA2-NF-κB信号轴调节人血小板活化和鼠肠系膜血管血栓形成的潜在调节剂

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines12081689
Chang, Yi; Hsia, Chih-Wei; Chiou, Kuan-Rau; Yen, Ting-Lin; Jayakumar, Thanasekaran; Sheu, Joen-Rong; Huang, Wei-Chieh
血小板
信号转导
NF-κB
心血管
Human
Mouse
cPLA2
发表日期：2024
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Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on (∙)OH Radicals and HO-1 Expression

哥伦比亚素通过抑制NF-κB/MAPKs通路，在体外减弱炎症反应并抑制肝损伤：对羟基自由基和HO-1表达的影响

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox10040553
Jayakumar, Thanasekaran; Hou, Shaw-Min; Chang, Chao-Chien; Fong, Tsorng-Harn; Hsia, Chih-Wei; Chen, Yen-Jen; Huang, Wei-Chieh; Saravanabhavan, Periyakali; Manubolu, Manjunath; Sheu, Joen-Rong; Hsia, Chih-Hsuan
炎症
炎症/感染
信号转导
NF-κB
MAPK/ERK
肝损伤
毒理研究
发表日期：2021
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The Antithrombotic Agent Pterostilbene Interferes with Integrin α(IIb)β(3)-Mediated Inside-Out and Outside-In Signals in Human Platelets

抗血栓药物紫檀芪干扰人血小板中整合素α(IIb)β(3)介导的由内而外和由外而内的信号传导

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms22073643
Huang, Wei-Chieh; Lin, Kao-Chang; Hsia, Chih-Wei; Hsia, Chih-Hsuan; Chen, Ting-Yu; Bhavan, Periyakali Saravana; Sheu, Joen-Rong; Hou, Shaw-Min
血小板
信号转导
Human
心血管
发表日期：2021
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Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin α(IIb)β(3) inside-out but not outside-in signals

哥伦比亚素对人血小板活化和体内血管血栓形成的调节：通过整合素α(IIb)β(3)由内而外而非由外而内的信号进行调节

期刊:Journal of Biomedical Science
影响因子:12.1
doi:10.1186/s12929-020-0619-5
Hou, Shaw-Min; Hsia, Chih-Wei; Tsai, Cheng-Lin; Hsia, Chih-Hsuan; Jayakumar, Thanasekaran; Velusamy, Marappan; Sheu, Joen-Rong
血小板
信号转导
心血管
发表日期：2020
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