Deubiquitinase USP24 activated by IL-6/STAT3 enhances PD-1 protein stability and suppresses T cell antitumor response.
IL-6/STAT3激活的去泛素化酶USP24增强PD-1蛋白稳定性并抑制T细胞抗肿瘤反应
期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adt4258
Hsieh Hung-Chia, Young Ming-Jer, Chen Kuan-Yu, Su Wu-Chou, Lin Chien-Chung, Yen Yi-Ting, Hung Jan-Jong, Wang Yi-Ching