日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors

鉴定和生物学评价苯并咪唑类化合物作为新型TGFβR1抑制剂

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2600746
Tseng, Hui-Ju; Wu, Yi-Wen; Chen, Yan-Ling; Lin, Tony Eight; Fang-Chin, Yu-Ting; Wu, Yueh-Lin; Sung, Tzu-Ying; Yen, Shih-Chung; Hsieh, Jui-Hua; Hsu, Kai-Cheng; Pan, Shiow-Lin
TGFβ
发表日期：2026
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Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment

结直肠癌治疗中PLK2抑制剂鉴定的共识药理学相互作用

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.5c02197
Wu, Yi-Wen; Yang, Chun-Lin; Lin, Tony Eight; Yeh, Yun-Hsuan; Fang-Chin, Yu-Ting; Sung, Tzu-Ying; Yen, Shih-Chung; Hsieh, Jui-Hua; Chung, Cheng-Chih; Pan, Shiow-Lin; Hsu, Kai-Cheng
肿瘤
肠癌
肿瘤免疫
发表日期：2026
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Power calculations for larval zebrafish in light-dark transition test for developmental neurotoxicity

斑马鱼幼体在光暗转换发育神经毒性试验中的功效计算

期刊:Neurotoxicology
影响因子:3.9
doi:10.1016/j.neuro.2025.103371
Konrad, Kathryn S; Allen-Moyer, Katherine; Ellis, Lee; Hessel, Ellen; Jaka, Oihane; Muriana, Arantza; Martínez, Beatriz Molina; Del Pozo, Ana; Schiavone, Valentina; Di Donato, Vincenzo; Sanz, Claudia Miguel; Truong, Lisa; Tanguay, Robyn; Shockley, Keith R; Ryan, Kristen; Hsieh, Jui-Hua
发育与干细胞
毒理研究
发表日期：2026
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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening.

利用基于结构的虚拟筛选方法鉴定和生物学评价一种靶向胰腺癌中选择性剪接的新型 CLK4 抑制剂

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202416323
Yang Chun-Lin, Wu Yi-Wen, Tu Huang-Ju, Yeh Yun-Hsuan, Lin Tony Eight, Sung Tzu-Ying, Li Mu-Chun, Yen Shih-Chung, Hsieh Jui-Hua, Yu Ming-Chin, Hsieh Sen-Yung, Hsieh Hsing-Pang, Pan Shiow-Lin, Hsu Kai-Cheng
肿瘤
胰腺癌
发表日期：2025
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Profiling of Environmental Mixtures Containing Metals for Their Toxicity Pathways and Mechanism of Action

对含金属环境混合物的毒性途径和作用机制进行分析

期刊:Environmental Science & Technology
影响因子:11.3
doi:10.1021/acs.est.4c07995
Ooka, Masato; Zhao, Jinghua; Zhang, Li; Huang, Ruili; Sakamuru, Srilatha; TeKrony, Charlotte; Hsieh, Jui-Hua; Collins, Bradley J; Dunnick, June K; Dixon, Darlene; Xia, Menghang
毒理研究
发表日期：2025
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Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening

利用基于结构的虚拟筛选鉴定高效 CDK8 抑制剂

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c02011
Lin, Tony Eight; Chou, Ching-Hsuan; Wu, Yi-Wen; Sung, Tzu-Ying; Hsu, Jui-Yi; Yen, Shih-Chung; Hsieh, Jui-Hua; Chang, Yu-Wei; Pan, Shiow-Lin; Huang, Wei-Jan; Hsu, Kai-Cheng; Yang, Chia-Ron
CDK8
发表日期：2025
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Establishment of an Integrated Model for Predicting Compound Mutagenicity with a Feature Importance Analysis

基于特征重要性分析的化合物致突变性预测综合模型的建立

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.5c01586
Yang, Chao-Hsu; Lin, Tony Eight; Hsieh, Jui-Hua; Hsu, Kai-Cheng; Chiueh, Pei-Te
毒理研究
发表日期：2025
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A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays

体外筛选试验基准浓度建模的生物统计学流程比较研究

期刊:Computational Toxicology
影响因子:2.9
doi:10.1016/j.comtox.2025.100360
Carstens, Kelly E; Dönmez, Arif; Hsieh, Jui-Hua; Bartmann, Kristina; Friedman, Katie Paul; Koch, Katharina; Scholze, Martin; Fritsche, Ellen
发表日期：2025
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Unlocking the Potential of Clustering and Classification Approaches: Navigating Supervised and Unsupervised Chemical Similarity

释放聚类和分类方法的潜力：驾驭监督式和非监督式化学相似性

期刊:Environmental Health Perspectives
影响因子:9.8
doi:10.1289/EHP14001
Mansouri, Kamel; Taylor, Kyla; Auerbach, Scott; Ferguson, Stephen; Frawley, Rachel; Hsieh, Jui-Hua; Jahnke, Gloria; Kleinstreuer, Nicole; Mehta, Suril; Moreira-Filho, José T; Parham, Fred; Rider, Cynthia; Rooney, Andrew A; Wang, Amy; Sutherland, Vicki
发表日期：2024
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An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors

集成机器学习模型生成一个针对性筛选库，用于识别 CDK8 抑制剂。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.5007
Lin, Tony Eight; Yen, Dyan; HuangFu, Wei-Chun; Wu, Yi-Wen; Hsu, Jui-Yi; Yen, Shih-Chung; Sung, Tzu-Ying; Hsieh, Jui-Hua; Pan, Shiow-Lin; Yang, Chia-Ron; Huang, Wei-Jan; Hsu, Kai-Cheng
CDK8
发表日期：2024
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