日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals

ATOH1、GFI1 和 POU4F3 介导的细胞重编程表明,表观遗传变化和细胞间信号传导是成熟哺乳动物毛细胞再生的障碍。

Amrita A Iyer ,Ishwar Hosamani ,John D Nguyen ,Tiantian Cai ,Sunita Singh ,Melissa M McGovern ,Lisa Beyer ,Hongyuan Zhang ,Hsin-I Jen ,Rizwan Yousaf ,Onur Birol ,Jenny J Sun ,Russell S Ray ,Yehoash Raphael ,Neil Segil ,Andrew K Groves

GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor

GFI1 通过充当 ATOH1 的非 DNA 转录辅激活剂和 DNA 结合阻遏物来调节毛细胞分化

Hsin-I Jen, Sunita Singh, Litao Tao, Helen R Maunsell, Neil Segil, Andrew K Groves

Combinatorial Atoh1 and Gfi1 induction enhances hair cell regeneration in the adult cochlea

Atoh1 和 Gfi1 的组合诱导增强成年耳蜗毛细胞再生

Sungsu Lee ,Jae-Jun Song ,Lisa A Beyer ,Donald L Swiderski ,Diane M Prieskorn ,Melih Acar ,Hsin-I Jen ,Andrew K Groves ,Yehoash Raphael

Transcriptomic and epigenetic regulation of hair cell regeneration in the mouse utricle and its potentiation by Atoh1

小鼠椭圆囊毛细胞再生的转录组和表观遗传调控及其由 Atoh1 增强

Hsin-I Jen, Matthew C Hill, Litao Tao, Kuanwei Sheng, Wenjian Cao, Hongyuan Zhang, Haoze V Yu, Juan Llamas, Chenghang Zong, James F Martin, Neil Segil, Andrew K Groves

An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment

Atoh1-S193A 磷酸突变等位基因导致听力障碍和运动障碍

Wei Rose Xie, Hsin-I Jen, Michelle L Seymour, Szu-Ying Yeh, Fred A Pereira, Andrew K Groves, Tiemo J Klisch, Huda Y Zoghbi

Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor

新生毛细胞转录组的表征和 Atoh1 转录因子直接靶标的识别

Tiantian Cai, Hsin-I Jen, Hyojin Kang, Tiemo J Klisch, Huda Y Zoghbi, Andrew K Groves

Reciprocal connectivity between mitral cells and external plexiform layer interneurons in the mouse olfactory bulb

小鼠嗅球中僧帽细胞与外丛状层中间神经元之间的相互连接

Longwen Huang, Isabella Garcia, Hsin-I Jen, Benjamin R Arenkiel

Clinical evaluation of CyberKnife in the treatment of vestibular schwannomas

CyberKnife治疗前庭神经鞘瘤的临床评价

Tsai, Jo-Ting; Lin, Jia-Wei; Lin, Chien-Min; Chen, Yuan-Hao; Ma, Hsin-I; Jen, Yee-Min; Chen, Yi-Hsun; Ju, Da-Tong