日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening.

利用基于结构的虚拟筛选方法鉴定和生物学评价一种靶向胰腺癌中选择性剪接的新型 CLK4 抑制剂

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202416323
Yang Chun-Lin, Wu Yi-Wen, Tu Huang-Ju, Yeh Yun-Hsuan, Lin Tony Eight, Sung Tzu-Ying, Li Mu-Chun, Yen Shih-Chung, Hsieh Jui-Hua, Yu Ming-Chin, Hsieh Sen-Yung, Hsieh Hsing-Pang, Pan Shiow-Lin, Hsu Kai-Cheng
肿瘤
胰腺癌
发表日期：2025
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Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer

揭示组织蛋白酶S在白细胞介素-7介导的抗肿瘤免疫中的调控机制，揭示其在口腔癌治疗中的靶向潜力

期刊:Journal of Biomedical Science
影响因子:9
doi:10.1186/s12929-025-01154-6
Yung-Chieh Chang,Szu-Jung Chen #,Shang-Hung Chen #,Sheng-Yen Hsiao,Li-Hsien Chen,Chung-Hsing Chen,Chan-Chuan Liu,Ya-Wen Chen,Ko-Jiunn Liu,Shang-Yin Wu,Jui-Mei Chu,Li-Ying Qiu,Wei-Fan Chiang,Hsing-Pang Hsieh,Wen-Yun Hsueh,Jenn-Ren Hsiao,Meng-Ru Shen,Jang-Yang Chang,Kwang-Yu Chang
口腔癌
细胞生物学
肿瘤
信号转导
免疫/内分泌
肿瘤免疫
发表日期：2025
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Noncovalent Interaction Effects on the Acyl Radical Reaction of Bicyclo[2.2.2]octanone: Selective Formation of Rearrangement and Cyclization Products

非共价相互作用对双环[2.2.2]辛酮酰基自由基反应的影响：重排和环化产物的选择性生成

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.5c01574
Chen, Chih-Ming; Kuo, Tung-Chun; Reddy, Julakanti Satyanarayana; Teoh, Yi Ning; Huang, Jyun-Sian; Lin, Sheng-Kuo; Cheng, Mu-Jeng; Hsieh, Hsing-Pang
发表日期：2025
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Integrating machine learning and protein-ligand interaction profiling for the discovery of METTL3 inhibitors

整合机器学习和蛋白质-配体相互作用分析以发现METTL3抑制剂

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-20634-1
Huang, Wei-Cheng; Hsieh, Hsing-Pang; Tung, Chun-Wei
MET
发表日期：2025
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Novel Naphthyridones Targeting Pannexin 1 for Colitis Management

针对 Pannexin 1 的新型萘啶酮用于治疗结肠炎

期刊:Advanced Science
影响因子:
doi:10.1002/advs.202411538
Wen-Yun Hsueh, Yi-Ling Wu, Meng-Tzu Weng, Shin-Yun Liu, Jascinta P Santavanond, Yi-Chung Liu, Ching-I Lin, Cheng-Nong Lai, Yi-Ru Lu, Jing Yin Hsu, Hong-Yu Gao, Jinq-Chyi Lee, Shu-Chen Wei, Ping-Chiang Lyu, Ivan K H Poon, Hsing-Pang Hsieh, Yu-Hsin Chiu0
免疫
肠炎
发表日期：2025
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Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function

靶向蛋白酶 S 促进 OLF1-BDNF/TrkB 轴激活以增强认知功能

期刊:Journal of Biomedical Science
影响因子:9
doi:10.1186/s12929-024-01037-2
Hao-Wei Lee #, Szu-Jung Chen #, Kuen-Jer Tsai, Kuei-Sen Hsu, Yi-Fan Chen, Chih-Hua Chang, Hsiao-Han Lin, Wen-Yun Hsueh, Hsing-Pang Hsieh, Yueh-Feng Lee, Huai-Chueh Chiang, Jang-Yang Chang0
AKT
发表日期：2024
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Influence of Ring Strain on the Formation of Rearrangement vs Cyclization Isotwistane Products in the Acyl Radical Reaction of Bicyclo[2.2.2]octanone

环张力对双环[2.2.2]辛酮酰基自由基反应中重排与环化异扭烷产物形成的影响

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.3c02374
Chen, Chih-Ming; Lin, Sheng-Kuo; Hsieh, Chi-Tien; Reddy, Julakanti Satyanarayana; Teoh, Yi Ning; Cheng, Mu-Jeng; Hsieh, Hsing-Pang
发表日期：2023
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A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

对当前新冠肺炎研究进展的关键概述：疫苗、抗病毒药物和治疗性抗体的研发

期刊:Journal of Biomedical Science
影响因子:12.1
doi:10.1186/s12929-022-00852-9
Kumari, Monika; Lu, Ruei-Min; Li, Mu-Chun; Huang, Jhih-Liang; Hsu, Fu-Fei; Ko, Shih-Han; Ke, Feng-Yi; Su, Shih-Chieh; Liang, Kang-Hao; Yuan, Joyce Pei-Yi; Chiang, Hsiao-Ling; Sun, Cheng-Pu; Lee, I-Jung; Li, Wen-Shan; Hsieh, Hsing-Pang; Tao, Mi-Hua; Wu, Han-Chung
肺炎
新冠
微生物学
发表日期：2022
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Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma

新型 FLT3/AURK 多激酶抑制剂对索拉非尼难治性和索拉非尼耐药性肝细胞癌有效

期刊:Journal of Biomedical Science
影响因子:9
doi:10.1186/s12929-022-00788-0
You-Liang Lai, Kai-Hung Wang, Hsing-Pang Hsieh, Wan-Ching Yen
免疫
细胞生物学
肝癌
肿瘤细胞
发表日期：2022
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Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer

天然产物杨梅素是一种泛 KDM4 抑制剂，其与聚乳酸-乙醇酸共聚物配方可有效靶向去势抵抗性前列腺癌

期刊:Journal of Biomedical Science
影响因子:9
doi:10.1186/s12929-022-00812-3
Jai-Shin Liu #, Wei-Kai Fang #, Shan-Min Yang, Meng-Chen Wu, Tsan-Jan Chen, Chih-Ming Chen, Tung-Yueh Lin, Kai-Lun Liu, Chien-Ming Wu, Yun-Ching Chen, Chih-Pin Chuu, Ling-Yu Wang, Hsing-Pang Hsieh, Hsing-Jien Kung, Wen-Ching Wang
肿瘤
前列腺癌
发表日期：2022
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