日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Disordered DNA-binding motif forms a modulation site for inhibiting the cancer immunotherapy target TREX1

无序的DNA结合基序形成一个调控位点，用于抑制癌症免疫治疗靶点TREX1。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1511
Huang, Kuan-Wei; Yu Tsai, Chieh-; Wu, Chia-Yun; Lin, Wei-Cheng; Wu, Meng-Tzu; Hsu, Kai-Cheng; Yu Yang, Chen-; Chang, I-Ya; Liu, Helene Minyi; Chu, Jhih-Wei; Hsiao, Yu-Yuan
信号转导
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors

鉴定和生物学评价苯并咪唑类化合物作为新型TGFβR1抑制剂

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2600746
Tseng, Hui-Ju; Wu, Yi-Wen; Chen, Yan-Ling; Lin, Tony Eight; Fang-Chin, Yu-Ting; Wu, Yueh-Lin; Sung, Tzu-Ying; Yen, Shih-Chung; Hsieh, Jui-Hua; Hsu, Kai-Cheng; Pan, Shiow-Lin
TGFβ
发表日期：2026
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Consensus Pharmacological Interactions for PLK2 Inhibitor Identification in Colorectal Cancer Treatment

结直肠癌治疗中PLK2抑制剂鉴定的共识药理学相互作用

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.5c02197
Wu, Yi-Wen; Yang, Chun-Lin; Lin, Tony Eight; Yeh, Yun-Hsuan; Fang-Chin, Yu-Ting; Sung, Tzu-Ying; Yen, Shih-Chung; Hsieh, Jui-Hua; Chung, Cheng-Chih; Pan, Shiow-Lin; Hsu, Kai-Cheng
肿瘤
肠癌
肿瘤免疫
发表日期：2026
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The crosstalk between acute hepatopancreatic necrosis disease (AHPND) and the Vibrio quorum sensing (QS) system: A review

急性肝胰腺坏死病（AHPND）与弧菌群体感应（QS）系统之间的相互作用：综述

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1013980
Wang, Hao-Ching; Kumar, Ramya; Ayenero, Michael Eniola; Hsu, Kai-Cheng; Lo, Chu-Fang; Lin, Shin-Jen; Wang, Han-Ching
微生物学
发表日期：2026
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Both semi-dwarf and photoperiod-insensitive traits in rice were important for the Green Revolution

水稻的半矮秆性和光周期不敏感性状对绿色革命都至关重要。

期刊:
影响因子:
doi:10.1186/s40529-026-00493-3
Wu, Cheng-Chieh; Tseng, Yi-Tzu; Huang, Lin-Tzu; Liu, Chun-Kai; Hsu, Kai-Cheng; Wang, Hao-Ching; Hsing, Yue-Ie Caroline; Chiou, Wan-Yi
发表日期：2026
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Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure-Based Virtual Screening.

利用基于结构的虚拟筛选方法鉴定和生物学评价一种靶向胰腺癌中选择性剪接的新型 CLK4 抑制剂

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202416323
Yang Chun-Lin, Wu Yi-Wen, Tu Huang-Ju, Yeh Yun-Hsuan, Lin Tony Eight, Sung Tzu-Ying, Li Mu-Chun, Yen Shih-Chung, Hsieh Jui-Hua, Yu Ming-Chin, Hsieh Sen-Yung, Hsieh Hsing-Pang, Pan Shiow-Lin, Hsu Kai-Cheng
肿瘤
胰腺癌
发表日期：2025
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Diversity and longitudinal records: Genetic architecture of disease associations and polygenic risk in the Taiwanese Han population

多样性和纵向记录：台湾汉族人群疾病关联和多基因风险的遗传结构

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adt0539
Liu, Ting-Yuan; Lu, Hsing-Fang; Chen, Yu-Chia; Liao, Chi-Chou; Lin, Ying-Ju; Yang, Jai-Sing; Liao, Wen-Ling; Lin, Wei-De; Chen, Shih-Yin; Huang, Yu-Chuen; Lin, Wei-Yong; Liu, Yu-Huei; Hsu, Kai-Cheng; Chang, Shih-Sheng; Chen, Hong-Da; Chou, Yu-Pao; Chang, Jan-Gowth; Wang, Chung-Hsing; Chang, Chwen-Tzuei; Huang, Chung-Ming; Yeo, Kai-Jieh; Wang, Tzu-Yuan; Yeh, Chin-Chung; Chen, Jiunn-Horng; Huang, Chi-Ping; Lai, Hsueh-Chou; Chen, Rong-Hsing; Lin, Hui-Ju; Wu, Po-Yuan; Wang, Jiu-Yao; Kuo, Chin-Chi; Cho, Der-Yang; Tsai, Chang-Hai; Tsai, Fuu-Jen
发表日期：2025
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USP24 upregulation stabilizes PKA-Cα to promote lipogenesis, inflammation, and fibrosis during MASH progression.

USP24 上调稳定 PKA-Cα，从而促进 MASH 进展过程中的脂肪生成、炎症和纤维化

期刊:Journal of Biomedical Science
影响因子:12.1
doi:10.1186/s12929-025-01148-4
Ning Beh, Wang Shao-An, Young Ming-Jer, Chen Yung-Ching, Hung Yun, Huong Tran Thu, Chang Wen-Chang, Wang Yi-Ching, Yu Ming-Lung, Hsu Kai-Cheng, Hung Jan-Jong
免疫/内分泌
炎症
发表日期：2025
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Exploring diarylheptanoid derivatives to target LIMK1 as potential agents against colorectal cancer

探索以LIMK1为靶点的二芳基庚烷衍生物作为潜在的结直肠癌治疗药物

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2583826
Chen, Liang-Chieh; Chang, Tung-Cheng; Tseng, Hui-Ju; Chu, Jung-Chun; Huang, Yun-Yi; Peng, Hao-Yuan; Kuo, Yi-Chen; Wu, Yi-Wen; Lin, Tony Eight; Yen, Shih-Chung; Hsu, Kai-Cheng; Huang, Wei-Jan; Pan, Shiow-Lin
肿瘤
肠癌
肿瘤免疫
LIMK1
发表日期：2025
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Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening

利用基于结构的虚拟筛选鉴定高效 CDK8 抑制剂

期刊:Journal of Chemical Information and Modeling
影响因子:5.3
doi:10.1021/acs.jcim.4c02011
Lin, Tony Eight; Chou, Ching-Hsuan; Wu, Yi-Wen; Sung, Tzu-Ying; Hsu, Jui-Yi; Yen, Shih-Chung; Hsieh, Jui-Hua; Chang, Yu-Wei; Pan, Shiow-Lin; Huang, Wei-Jan; Hsu, Kai-Cheng; Yang, Chia-Ron
CDK8
发表日期：2025
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