A multi-faceted discovery strategy identifies functional antibodies binding to cysteine-rich domain 1 of hDKK1 for cancer immunotherapy via Wnt non-canonical pathway.
一项多方面的发现策略，通过 Wnt 非经典途径，鉴定出与 hDKK1 的富含半胱氨酸的结构域 1 结合的功能性抗体，用于癌症免疫治疗
期刊:Oncogene
影响因子:7.3
doi:10.1038/s41388-025-03445-6
Wang Linya, Peterson Sean M, Yang Marisa, Lujan Hernandez Ana G, Yuan Tom Z, Han Zhen, Prabhu Vishwas, Chan Kara Y, Hu Cameron F, Villalta Mouna, Htoy Tammy, VanDyke Paul, Holliday Carson, Franco Hector, Wadhwa Hansika, Giang Hoa, Stafford Ryan, Axelrod Fumiko, Sato Aaron
