Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core
基于咪唑并[1,2-a]吡嗪核心结构,发现了一种强效的、可注射的Aurora激酶抑制剂
期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/ml100063w
Yu, Tao; Tagat, Jayaram R; Kerekes, Angela D; Doll, Ronald J; Zhang, Yonglian; Xiao, Yushi; Esposite, Sara; Belanger, David B; Curran, Patrick J; Mandal, Amit K; Siddiqui, M Arshad; Shih, Neng-Yang; Basso, Andrea D; Liu, Ming; Gray, Kimberly; Tevar, Seema; Jones, Jennifer; Lee, Suining; Liang, Lianzhu; Ponery, Samad; Smith, Elizabeth B; Hruza, Alan; Voigt, Johannes; Ramanathan, Lata; Prosise, Winifred; Hu, Mengwei