日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation

强效且选择性的LSD1抑制剂DC551040揭示了一种有前景的AML联合疗法，并有助于深入了解表观遗传失调。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-026-02637-0
Wang, Jiang; Wang, Hanlin; Du, Runhua; Li, Chunpu; Su, Mingbo; Wang, Shuni; Kan, Weijuan; Liu, Guobin; Zhang, Yu; Hu, Xiaobei; Gao, Feng; Xu, Gaoya; Li, Cong; Zhu, Wei; Ye, Yunfei; Sheng, Li; Shi, Yuqiang; Shao, Yingying; Song, Jiangzhou; Wang, Yuxian; Wang, Bo; Zhou, Yubo; Huang, He; Li, Jia; Liu, Hong
LSD1
表观遗传
发表日期：2026
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Transient mechanical activation of the Piezo1 channel facilitates ex vivo expansion of hematopoietic stem cells

Piezo1通道的瞬时机械激活促进了造血干细胞的体外扩增

期刊:Cell Research
影响因子:25.9
doi:10.1038/s41422-025-01209-1
Wang, Qiwei; Zeng, Xin; Yang, Haoxiang; Lu, Huan; Jiang, Lingli; Xu, Lizhen; Li, Jinxin; Li, Jingyi; Han, Yingli; Wu, Xiaoyan; Zhou, Yuanhong; Chen, Xiaolan; Zhao, Yanmin; Shi, Jimin; Luo, Yi; Ni, Fang; Sun, Jie; Zhao, Qian; Yang, Fan; Xia, Peng; Jiang, Hongyuan; Huang, He; Qian, Pengxu
细胞生物学
发育与干细胞
干细胞
发表日期：2026
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Apolipoprotein E knockout attenuates vascular graft fibrosis by reducing profibrotic macrophage formation through low-density lipoprotein receptor related protein 1.

载脂蛋白 E 敲除通过低密度脂蛋白受体相关蛋白 1 减少促纤维化巨噬细胞的形成，从而减轻血管移植纤维化。

期刊:Bioactive Materials
影响因子:20.3
doi:10.1016/j.bioactmat.2026.01.029
Fu Jiayin, Zhao Meng, Zhao Jing, Wu Shaofei, Wu Jiahui, Hong Xulin, Huang He, Fu Guosheng, Xu Shengjie
细胞生物学
巨噬细胞
巨噬细胞
发表日期：2026
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STING synergizes with TOX suppressing HO-1 expression to trigger ferroptosis in tumor-infiltrating CD8+ T cell and immunotherapy resistance

STING 与 TOX 协同抑制 HO-1 表达，从而诱导肿瘤浸润 CD8+ T 细胞发生铁死亡，并导致免疫治疗耐药。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69350-y
Zhu, Qian; Zhang, Jun-Bao; Nie, Cai-Ping; Liu, Xiu-Feng; Zhan, Liang-Ping; Li, Ming; Zeng, Xi-Liang; He, Jia; Huang, He; Xia, Xiao-Jun; Gao, Song; Zhang, Xiao-Shi; Li, Jiang
肿瘤
T细胞
肿瘤免疫
STING
治疗耐药
CD8
铁死亡
TOX
细胞生物学
免疫/内分泌
发表日期：2026
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TET1 as a master regulator controlling GPX4-dependent and -independent ferroptosis surveillance in acute myeloid leukemia.

TET1 作为控制急性髓系白血病中 GPX4 依赖性和非依赖性铁死亡监视的主调节因子。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68509-x
Yang Lingling, Lu Jun, Yun Weina, Yang Xinquan, Sun Jie, Ge Chaodong, Han Fei, Li Xiang, Min Junxia, Huang He, Wang Fudi, Jiang Xi
白血病
GPX4
铁死亡
发表日期：2026
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Development and validation of a predictive model for extranodal natural killer/T-cell lymphoma

结外自然杀伤/T细胞淋巴瘤预测模型的建立与验证

期刊:npj Digital Medicine
影响因子:15.1
doi:10.1038/s41746-025-02316-4
Li, Shuo; Gao, Li-Min; Hong, Huang-Ming; Zhong, Yu-Jia; Cai, Qing-Qing; Huang, Hui-Qiang; Li, Zhi-Ming; Huang, He; Zheng, Yin-Li; Zeng, Xuan-Kai; Feng, Yan-Fen; Zhang, Ying-Chun; Zang, Sheng-Bing; Li, Yan; Yun, Jing-Ping; Huang, Yu-Hua
T细胞
淋巴瘤
T细胞
细胞生物学
免疫/内分泌
发表日期：2026
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Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

星形胶质细胞SREBP2下调介导的神经元胆固醇缺乏，通过损害海马突触可塑性和兴奋性突触传递，导致术后认知功能障碍。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202519874
Huang, He; Zhou, Chenrui; Chen, Chen; Tang, Huimei; Dong, Wei; Wan, Jie; Kang, Weiye; Sun, Ao; Liu, Yiqi; Jin, Chunhui; Lyu, Xiaobin; Zhu, Yankun; Zhou, Chenghua; Wu, Yuqing
胶质细胞
EBP
神经科学
代谢
细胞生物学
Hippo
发表日期：2026
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Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug-Resistant Candida albicans

基于二态性的合成致死疗法治疗耐药性白色念珠菌系统性感染

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202518196
Gao, Yang; Su, Jiahe; Yuan, Jiawei; Cao, Qinyan; Wu, Yue; Xiao, Yuyang; Yang, Guang; Xia, Ruomu; Yang, Jingpeng; Li, Yanan; Wu, Lina; Huang, He; Meng, Lingtong
炎症/感染
治疗耐药
发表日期：2026
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Covalent capture and genetic code expansion enables chemoproteomic profiling and functional characterization of lysine acetoacetylation.

共价捕获和遗传密码扩展能够对赖氨酸乙酰乙酰化进行化学蛋白质组学分析和功能表征。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.aeb5106
Song Xiaohan, Lu Yuhan, Guo Xinlong, Zheng Yanan, Huang He
乙酰化
表观遗传
发表日期：2026
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Maternal gut microbiota mediates prenatal stress-induced fetal blood‒brain barrier dysfunction.

母体肠道菌群介导产前应激引起的胎儿血脑屏障功能障碍。

期刊:Gut Microbes
影响因子:11
doi:10.1080/19490976.2026.2631242
Wang Xuanping, Zhou Fang-Yue, Wu Ting, Duan Chenchi, Luo Xukai, Meng Yicong, Huang He-Feng, Wu Yan-Ting
血脑屏障
发育与干细胞
肠道菌群
发表日期：2026
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