Huang Kevin相关文献与解析，生知库 | 链接生命科学的每一步

Boeckman, Mike; Drabison, Thomas; Germakovski, Arthur; Warmuth, Allison; Ahmed, Bagdad; Chowdhury, Anika T; Hu, Shuiying; Sprowl, Jason A; Sparreboom, Alex; Huang, Kevin M

毒理研究

发表日期：2026

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A new highly oxygen-deficient and cubic Pr(3)ZrO(8-δ) for intermediate-temperature thermochemical production of oxygen and hydrogen

一种新型高氧缺陷立方相Pr(3)ZrO(8-δ)材料，可用于中温热化学制取氧气和氢气。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-026-69235-0

Lu, Jiaxin; Zhang, Yongliang; Chen, Luhong; Chen, Yan; An, Ke; Shoukry, Yasser; Jin, Xinfang; Wang, Zhi-Hao; Mu, Sai; Lei, Xueling; Huang, Kevin

发表日期：2026

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Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.

靶向 ENO1 可重编程巨噬细胞极化，从而触发抗肿瘤免疫，并提高放射疗法的治疗效果。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-026-08416-7

Lin Yu-Sen, Chang Hsin-Yu, Hong Wei-Ze, Chen Jhen-Yu, Huang Wei-Ching, Yuan Ta-Tung, Ke Tao-Wei, Tsai Yuan-Yao, Chen Te-Hong, Liang Ji-An, Chao Jui-I, Chao K S Clifford, Huang Kevin Chih-Yang

Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer.

MicroRNA-29b 的缺失促进 DNMT3b 介导的 STING 下调，从而减弱 KRAS 突变型结直肠癌中放射治疗诱导的抗肿瘤免疫。

期刊:npj Precision Oncology

影响因子:8

doi:10.1038/s41698-026-01290-8

Chang Hsin-Yu, Chen Jhen-Yu, Ke Tao-Wei, Jiang Yi-Wen, Hong Wei-Ze, Tsai Yuan-Yao, Chiang Shu-Fen, Lin Yu-Sen, Huang Chi-Hsien, Chen Te-Hong, Chao K S Clifford, Huang Kevin Chih-Yang

VASCilia is an open-source, deep learning-based tool for 3D analysis of cochlear hair cell stereocilia bundles

VASCilia 是一款基于深度学习的开源工具，用于对耳蜗毛细胞立体纤毛束进行 3D 分析。

期刊:PLoS Biology

影响因子:7.2

doi:10.1371/journal.pbio.3003591

Kassim, Yasmin M; Rosenberg, David B; Das, Samprita; Wang, Xiaobo; Huang, Zhuoling; Rahman, Samia; Al Shammaa, Ibraheem M; Salim, Samer; Huang, Kevin; Renero, Alma; Ninoyu, Yuzuru; Friedman, Rick A; Indzhykulian, Artur A; Manor, Uri

Uncovering dual molecular diagnoses in families with complex phenotypes through structural and clinical studies of novel COL4A6 variants

通过对新型 COL4A6 变异体的结构和临床研究，揭示具有复杂表型家族的双重分子诊断

期刊:Qjm-An International Journal of Medicine

影响因子:6.4

doi:10.1093/qjmed/hcaf246

Owrang, Daniel; Rad, Aboulfazl; Cretu, Constantin; Lin, Sheng-Jia; Mustafa, Hafiz Muhammad; Huang, Kevin; Waheed, Nadia; Hussain, Maqbool; Riaz, Sadia; Preobraschenski, Julia; Varshney, Gaurav K; Oprea, Gabriela; Vona, Barbara

COL

发表日期：2026

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Heterologous prime-boost immunization of AAV-based neoantigen cancer vaccine induces anti-tumor immunity to inhibit tumor growth and relapse.

基于 AAV 的新抗原癌症疫苗的异源初免-加强免疫可诱导抗肿瘤免疫，从而抑制肿瘤生长和复发。

期刊:Cancer Immunology Immunotherapy

影响因子:5.1

doi:10.1007/s00262-026-04336-9

Huang Chi-Hsien, Chen Jhen-Yu, Chang Hsin-Yu, Hong Wei-Ze, Jiang Yi-Wen, Lee Chien-Yueh, Wu Chia-Hsin, Lin Yu-Sen, Tsai Yuan-Yao, Kao Wei-Ling, Chao K S Clifford, Huang Kevin Chih-Yang

OATP2B1 Deficiency Ameliorates Irinotecan-Induced Gastrointestinal Toxicity

OATP2B1 缺乏可减轻伊立替康引起的胃肠道毒性

期刊:Cts-Clinical and Translational Science

影响因子:2.8

doi:10.1111/cts.70452

Taheri, Hanieh; de Bruijn, Peter; Li, Yang; Kleinert, Nicholas R; Corps, Kara N; Mathijssen, Ron H J; Huang, Kevin M; Sparreboom, Alex; Hu, Shuiying

Rationally Designed TadA-Derived Cytosine Editors Enable Context-Independent Zebrafish Genome Editing

合理设计的TadA衍生胞嘧啶编辑器实现了与上下文无关的斑马鱼基因组编辑

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202509800

Qin, Wei; Lin, Sheng-Jia; Zhang, Yu; Huang, Kevin; Petree, Cassidy; Boyd, Kevin; Varshney, Pratishtha; Varshney, Gaurav K

发表日期：2025

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Optimizing gRNA selection for high-penetrance F0 CRISPR screening for interrogating disease gene function.

优化 gRNA 选择，以进行高渗透性 F0 CRISPR 筛选，从而探究疾病基因功能

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkaf180

Lin Sheng-Jia, Huang Kevin, Petree Cassidy, Qin Wei, Varshney Pratishtha, Varshney Gaurav K

其它

发表日期：2025

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Role of solute carrier transporters in the biodistribution and toxicity of chemotherapeutic drugs

溶质载体转运蛋白在化疗药物生物分布和毒性中的作用

A new highly oxygen-deficient and cubic Pr(3)ZrO(8-δ) for intermediate-temperature thermochemical production of oxygen and hydrogen

一种新型高氧缺陷立方相Pr(3)ZrO(8-δ)材料，可用于中温热化学制取氧气和氢气。

Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.

靶向 ENO1 可重编程巨噬细胞极化，从而触发抗肿瘤免疫，并提高放射疗法的治疗效果。

Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer.

MicroRNA-29b 的缺失促进 DNMT3b 介导的 STING 下调，从而减弱 KRAS 突变型结直肠癌中放射治疗诱导的抗肿瘤免疫。

VASCilia is an open-source, deep learning-based tool for 3D analysis of cochlear hair cell stereocilia bundles

VASCilia 是一款基于深度学习的开源工具，用于对耳蜗毛细胞立体纤毛束进行 3D 分析。

Uncovering dual molecular diagnoses in families with complex phenotypes through structural and clinical studies of novel COL4A6 variants

通过对新型 COL4A6 变异体的结构和临床研究，揭示具有复杂表型家族的双重分子诊断

Heterologous prime-boost immunization of AAV-based neoantigen cancer vaccine induces anti-tumor immunity to inhibit tumor growth and relapse.

基于 AAV 的新抗原癌症疫苗的异源初免-加强免疫可诱导抗肿瘤免疫，从而抑制肿瘤生长和复发。

OATP2B1 Deficiency Ameliorates Irinotecan-Induced Gastrointestinal Toxicity

OATP2B1 缺乏可减轻伊立替康引起的胃肠道毒性

Rationally Designed TadA-Derived Cytosine Editors Enable Context-Independent Zebrafish Genome Editing

合理设计的TadA衍生胞嘧啶编辑器实现了与上下文无关的斑马鱼基因组编辑

Optimizing gRNA selection for high-penetrance F0 CRISPR screening for interrogating disease gene function.

优化 gRNA 选择，以进行高渗透性 F0 CRISPR 筛选，从而探究疾病基因功能