ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
ILF3 通过稳定 SLC3A2 mRNA 来增强半胱氨酸的摄取和 GSH 的合成,从而促进结直肠癌细胞对铁死亡的抵抗力
期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07872-x
Wang Shuhao, Zhu Lu, Wang Yubing, Han Yue, Wang Qingkun, Yang Wenqing, Zhao Lei, Zhang Yu, Pei Delong, Huang Wankun, Jin Aihua, Lin Zhenhua, Piao Junjie