Multi-omics analysis elucidates the therapeutic mechanisms of the Quzhi formula in metabolic dysfunction-associated steatohepatitis targeting gut microbiota, lipid metabolism, and the role of its metabolite fraxin
多组学分析阐明了曲芝方治疗代谢功能障碍相关性脂肪性肝炎的机制,其靶点包括肠道菌群、脂质代谢及其代谢产物白蜡苷的作用。
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1694242
Wu, Jiao-Xiang; Wu, Yue-Lan; Li, Mei-Fang; Liu, Nian; Liu, Ying; Huang, Yan-Ping; Gan, Yuan; Wang, Xiao-Yu; Chai, Hai-Sheng; Xu, Jin; Xi, Qian; Guo, Xi-Rong; Sheng, Hui-Ming; Shen, Ting-Ting; Zhang, Qin