Huang Yu-Ming M相关文献与解析，生知库 | 链接生命科学的每一步

Lipid droplet targeting of the lipase coactivator ABHD5 and the fatty liver disease-causing variant PNPLA3 I148M is required to promote liver steatosis.

脂肪酶共激活因子 ABHD5 和导致脂肪肝疾病的变异体 PNPLA3 I148M 靶向脂滴是促进肝脏脂肪变性的必要条件

doi:10.1016/j.jbc.2025.108186

Teskey Grace, Tiwari Nivedita, Butcko Andrew J, Kumar Amit, Yadav Anuradha, Huang Yu-Ming M, Kelly Christopher V, Granneman James G, Perfield James W, Mottillo Emilio P

其它

发表日期：2025

文献求助收藏

In Silico Discovery of Potential Inhibitors Targeting the MEIG1-PACRG Complex for Male Contraceptive Development

利用计算机模拟发现靶向MEIG1-PACRG复合物的潜在抑制剂，用于男性避孕药的研发

期刊:Proteins-Structure Function and Bioinformatics

影响因子:2.8

doi:10.1002/prot.26829

Hasse, Timothy; Zhang, Zhibing; Huang, Yu-Ming M

发表日期：2025

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Unraveling the Molecular Mechanisms of ABHD5 Membrane Targeting

揭示ABHD5膜靶向的分子机制

期刊:

影响因子:

doi:10.1101/2025.05.06.652485

Kumar, Amit; Sanders, Matthew; Zhang, Huamei; Zhou, Li; Parveen, Shahnaz; Kelly, Christopher V; Granneman, James G; Huang, Yu-Ming M

ABHD5

发表日期：2025

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Mechanistic insights into ligand dissociation from the SARS-CoV-2 spike glycoprotein

对SARS-CoV-2刺突糖蛋白配体解离机制的深入研究

期刊:PLoS Computational Biology

影响因子:3.6

doi:10.1371/journal.pcbi.1011955

Hasse, Timothy; Mantei, Esra; Shahoei, Rezvan; Pawnikar, Shristi; Wang, Jinan; Miao, Yinglong; Huang, Yu-Ming M

SARS-CoV-2

发表日期：2024

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MIXED METHODS INTERVENTION DEVELOPMENT OF A TELEREHABILITATION PROGRAM FOR OLDER VETERANS

混合方法干预：开发面向老年退伍军人的远程康复项目

期刊:

影响因子:

doi:10.1101/2024.12.16.628759

Hasse, Timothy; Zhang, Zhibing; Huang, Yu-Ming M; Rauzi, Michelle; Stevens-Lapsley, Jennifer

发表日期：2024

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Molecular dynamics study reveals key disruptors of MEIG1-PACRG interaction

分子动力学研究揭示了MEIG1-PACRG相互作用的关键干扰因子

期刊:Proteins-Structure Function and Bioinformatics

影响因子:2.8

doi:10.1002/prot.26449

Hasse, Timothy; Zhang, Zhibing; Huang, Yu-Ming M

发表日期：2023

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Molecular Modeling of ABHD5 Structure and Ligand Recognition

ABHD5结构及配体识别的分子建模

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2022.935375

Shahoei, Rezvan; Pangeni, Susheel; Sanders, Matthew A; Zhang, Huamei; Mladenovic-Lucas, Ljiljana; Roush, William R; Halvorsen, Geoff; Kelly, Christopher V; Granneman, James G; Huang, Yu-Ming M

ABHD5

发表日期：2022

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Gaussian accelerated molecular dynamics (GaMD): principles and applications

高斯加速分子动力学（GaMD）：原理与应用

期刊:Wiley Interdisciplinary Reviews-Computational Molecular Science

影响因子:27

doi:10.1002/wcms.1521

Wang, Jinan; Arantes, Pablo R; Bhattarai, Apurba; Hsu, Rohaine V; Pawnikar, Shristi; Huang, Yu-Ming M; Palermo, Giulia; Miao, Yinglong

发表日期：2021

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Multiscale computational study of ligand binding pathways: Case of p38 MAP kinase and its inhibitors

配体结合通路的多尺度计算研究：以p38 MAP激酶及其抑制剂为例

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2021.08.026

Multiscale Analysis of PNPLA2 and PNPLA3 Membrane Targeting

PNPLA2和PNPLA3膜靶向的多尺度分析

Lipid droplet targeting of the lipase coactivator ABHD5 and the fatty liver disease-causing variant PNPLA3 I148M is required to promote liver steatosis.

脂肪酶共激活因子 ABHD5 和导致脂肪肝疾病的变异体 PNPLA3 I148M 靶向脂滴是促进肝脏脂肪变性的必要条件

In Silico Discovery of Potential Inhibitors Targeting the MEIG1-PACRG Complex for Male Contraceptive Development

利用计算机模拟发现靶向MEIG1-PACRG复合物的潜在抑制剂，用于男性避孕药的研发

Unraveling the Molecular Mechanisms of ABHD5 Membrane Targeting

揭示ABHD5膜靶向的分子机制

Mechanistic insights into ligand dissociation from the SARS-CoV-2 spike glycoprotein

对SARS-CoV-2刺突糖蛋白配体解离机制的深入研究

MIXED METHODS INTERVENTION DEVELOPMENT OF A TELEREHABILITATION PROGRAM FOR OLDER VETERANS

混合方法干预：开发面向老年退伍军人的远程康复项目

Molecular dynamics study reveals key disruptors of MEIG1-PACRG interaction

分子动力学研究揭示了MEIG1-PACRG相互作用的关键干扰因子

Molecular Modeling of ABHD5 Structure and Ligand Recognition

ABHD5结构及配体识别的分子建模

Gaussian accelerated molecular dynamics (GaMD): principles and applications

高斯加速分子动力学（GaMD）：原理与应用

Multiscale computational study of ligand binding pathways: Case of p38 MAP kinase and its inhibitors

配体结合通路的多尺度计算研究：以p38 MAP激酶及其抑制剂为例