Therapeutic Prime/Pull Vaccination of HSV-2 Infected Guinea Pigs with the Ribonucleotide Reductase 2 (RR2) Protein and CXCL11 Chemokine Boosts Antiviral Local Tissue-Resident and Effector Memory CD4+ and CD8+ T Cells and Protects Against Recurrent Genital Herpes
使用核糖核苷酸还原酶 2 (RR2) 蛋白和 CXCL11 趋化因子对 HSV-2 感染的豚鼠进行治疗性引发/拉动疫苗接种,可增强抗病毒局部组织驻留和效应记忆 CD4+ 和 CD8+ T 细胞,并预防复发性生殖器疱疹
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doi:10.1101/2023.08.08.552454
Afshana Quadiri, Swayam Prakash, Nisha Rajeswari Dhanushkodi, Mahmoud Singer, Latifa Zayou, Amin Mohammed Shaik, Miyo Sun, Berfin Suzer, Lauren Lau, Amruth Chilukurri, Hawa Vahed, Hubert Schaefer, Lbachir BenMohamed