日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities

鞘内注射9型腺相关病毒载体后非人灵长类动物组织转录组的变化:对器官毒性的深入了解

Aihara, Fumiaki; Mardo, Matthew; Ruda, Vera; Rio, Tony Del; Bigot, Karine; Singer, Jochen; Onishi-Seebacher, Megumi; Couttet, Philippe; Mansfield, Keith; Hudry, Eloise

Impact of pre-existing immunity on safety and biodistribution of a single AAV9 vectorintrathecal injection in cynomolgus monkeys.

既往免疫对食蟹猴单次鞘内注射 AAV9 载体的安全性和生物分布的影响。

Vono Maria, Rio Tony Del, Magdaleno Eduardo, Loll Nathalie R, Jarvis Philip, Walter Catherine, Kikkawa Rie, Mansfield Keith, McBlane Fraser, Sirivelu Madhu P, Ozsolak Fatih, Brees Dominique, Hudry Eloise, Rubic-Schneider Tina, Tukov Francis Fonyuy, Huang Guanrong

Liver injury in cynomolgus monkeys following intravenous and intrathecal scAAV9 gene therapy delivery.

食蟹猴经静脉和鞘内注射 scAAV9 基因治疗后出现肝损伤

Hudry Eloise, Aihara Fumiaki, Meseck Emily, Mansfield Keith, McElroy Cameron, Chand Deepa, Tukov Francis Fonyuy, Penraat Kelley

Neurofilament light chain and dorsal root ganglia injury after adeno-associated virus 9 gene therapy in nonhuman primates

非人灵长类动物腺相关病毒9基因治疗后神经丝轻链和背根神经节损伤

Johnson, Eric W; Sutherland, Jeffrey J; Meseck, Emily; McElroy, Cameron; Chand, Deepa H; Tukov, Francis Fonyuy; Hudry, Eloise; Penraat, Kelley

Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques

鞘内注射sc-AAV9-CB-GFP:食蟹猴单次给药后以全身分布为主

Meseck, Emily K; Guibinga, Ghiabe; Wang, Stephen; McElroy, Cameron; Hudry, Eloise; Mansfield, Keith

Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer's disease

APOE等位基因对正常衰老和阿尔茨海默病中神经胶质细胞转录组的影响

Serrano-Pozo, Alberto; Li, Zhaozhi; Noori, Ayush; Nguyen, Huong N; Mezlini, Aziz; Li, Liang; Hudry, Eloise; Jackson, Rosemary J; Hyman, Bradley T; Das, Sudeshna

Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation

糖原合成酶激酶-3β (GSK-3β) 的亚型选择性降低可减少突触 tau 蛋白的磷酸化、跨细胞扩散和聚集。

Amaral, Ana Claudia; Perez-Nievas, Beatriz G; Siao Tick Chong, Michael; Gonzalez-Martinez, Alicia; Argente-Escrig, Herminia; Rubio-Guerra, Sara; Commins, Caitlin; Muftu, Serra; Eftekharzadeh, Bahareh; Hudry, Eloise; Fan, Zhanyun; Ramanan, Prianca; Takeda, Shuko; Frosch, Matthew P; Wegmann, Susanne; Gomez-Isla, Teresa

Therapeutic AAV Gene Transfer to the Nervous System: A Clinical Reality

治疗性腺相关病毒(AAV)基因转移至神经系统:临床现实

Hudry, Eloise; Vandenberghe, Luk H

Efficient Gene Transfer to the Central Nervous System by Single-Stranded Anc80L65

利用单链Anc80L65高效基因转移至中枢神经系统

Hudry, Eloise; Andres-Mateos, Eva; Lerner, Eli P; Volak, Adrienn; Cohen, Olivia; Hyman, Bradley T; Maguire, Casey A; Vandenberghe, Luk H

In Vivo Two Photon Imaging of Astrocytic Structure and Function in Alzheimer's Disease

阿尔茨海默病中星形胶质细胞结构和功能的体内双光子成像

Kelly, Patricia; Hudry, Eloise; Hou, Steven S; Bacskai, Brian J