日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intracrine FFA4 signaling controls lipolysis at lipid droplets.

细胞内 FFA4 信号传导控制脂滴处的脂肪分解。

O'Brien Shannon L, Tripp Emma, Barki Natasja, Blondel-Tepaz Elodie, Smith Gabrielle, Boufersaoui Adam, Roberts Jennie, Pike Jeremy A, Correia Joao, Miljus Tamara, Bouvier Michel, Tennant Daniel A, Hudson Brian D, Gerhart-Hines Zachary, Milligan Graeme, Schwartz Thue W, Calebiro Davide

Multicolored sequential resonance energy transfer for detection of simultaneous ligand binding at G protein-coupled receptors.

多色顺序共振能量转移检测G蛋白偶联受体上配体同时结合

Valentini Alice, Dibnah Bethany, Ciba Marija, Duncan Elaine M, Manandhar Asmita, Strellis Bethany, Vita Luca, Lucianno Olivia, Massey Conor, Coe Sophie, Ulven Trond, Hudson Brian D, Rexen Ulven Elisabeth

Metabolite-sensing GPCRs controlling interactions between adipose tissue and inflammation

代谢物感应GPCR控制脂肪组织与炎症之间的相互作用

Duncan, Elaine M; Vita, Luca; Dibnah, Bethany; Hudson, Brian D

Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease

M1毒蕈碱受体偏向性突变小鼠表现出朊病毒神经退行性疾病进展加速。

Scarpa, Miriam; Molloy, Colin; Jenkins, Laura; Strellis, Bethany; Budgett, Rebecca F; Hesse, Sarah; Dwomoh, Louis; Marsango, Sara; Tejeda, Gonzalo S; Rossi, Mario; Ahmed, Zeshan; Milligan, Graeme; Hudson, Brian D; Tobin, Andrew B; Bradley, Sophie J

Receptor selectivity between the G proteins Gα(12) and Gα(13) is defined by a single leucine-to-isoleucine variation

G蛋白Gα(12)和Gα(13)之间的受体选择性是由单个亮氨酸到异亮氨酸的变异决定的。

Mackenzie, Amanda E; Quon, Tezz; Lin, Li-Chiung; Hauser, Alexander S; Jenkins, Laura; Inoue, Asuka; Tobin, Andrew B; Gloriam, David E; Hudson, Brian D; Milligan, Graeme

FFA4/GPR120: Pharmacology and Therapeutic Opportunities

FFA4/GPR120:药理学和治疗机遇

Milligan, Graeme; Alvarez-Curto, Elisa; Hudson, Brian D; Prihandoko, Rudi; Tobin, Andrew B

Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance

脂肪酸16:4(n-3)可刺激脾脏巨噬细胞中GPR120诱导的信号级联反应,从而促进化疗耐药性。

Houthuijzen, Julia M; Oosterom, Ilse; Hudson, Brian D; Hirasawa, Akira; Daenen, Laura G M; McLean, Chelsea M; Hansen, Steffen V F; van Jaarsveld, Marijn T M; Peeper, Daniel S; Jafari Sadatmand, Sahar; Roodhart, Jeanine M L; van de Lest, Chris H A; Ulven, Trond; Ishihara, Kenji; Milligan, Graeme; Voest, Emile E

Treatment of type 2 diabetes by free Fatty Acid receptor agonists

利用游离脂肪酸受体激动剂治疗2型糖尿病

Watterson, Kenneth R; Hudson, Brian D; Ulven, Trond; Milligan, Graeme

The molecular basis of ligand interaction at free fatty acid receptor 4 (FFA4/GPR120)

游离脂肪酸受体 4 (FFA4/GPR120) 配体相互作用的分子基础

Hudson, Brian D; Shimpukade, Bharat; Milligan, Graeme; Ulven, Trond

Concomitant action of structural elements and receptor phosphorylation determines arrestin-3 interaction with the free fatty acid receptor FFA4

结构元件和受体磷酸化的协同作用决定了阻遏蛋白-3与游离脂肪酸受体FFA4的相互作用。

Butcher, Adrian J; Hudson, Brian D; Shimpukade, Bharat; Alvarez-Curto, Elisa; Prihandoko, Rudi; Ulven, Trond; Milligan, Graeme; Tobin, Andrew B