Hughes Jonathan R相关文献与解析，生知库

Fabbrizi Maria Rita, Hughes Jonathan R, Punshon Leah D, Hawkins Laura, Sorokin Vasily, Ormrod Alice, Melia Emma, Vaidya Karthik, Rubbi Carlos P, Phoenix Ben, Hill Mark A, Parsons Jason L

其它

发表日期：2025

文献求助收藏

Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia

自噬是轻度缺氧条件下头颈部鳞状细胞癌（HNSCC）细胞放射抗性的主要驱动因素。

期刊:Journal of Cellular and Molecular Medicine

影响因子:4.2

doi:10.1111/jcmm.18482

Hill, Rhianna M; Li, Chun; Hughes, Jonathan R; Rocha, Sonia; Grundy, Gabrielle J; Parsons, Jason L

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

PARP抑制剂增强头颈部鳞状细胞癌3D球体放射敏感性的有效性

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2022.940377

Zhou, Chumin; Fabbrizi, Maria Rita; Hughes, Jonathan R; Grundy, Gabrielle J; Parsons, Jason L

MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance

MEK1/2 抑制剂停药可逆转由 BRAFV600E 扩增驱动的获得性耐药性，而 KRASG13D 扩增则促进 EMT 化学耐药性

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-019-09438-w

Matthew J Sale, Kathryn Balmanno, Jayeta Saxena, Eiko Ozono, Katarzyna Wojdyla, Rebecca E McIntyre, Rebecca Gilley, Anna Woroniuk, Karen D Howarth, Gareth Hughes, Jonathan R Dry, Mark J Arends, Pilar Caro, David Oxley, Susan Ashton, David J Adams, Julio Saez-Rodriguez, Paul D Smith, Simon J Cook1

AROS

发表日期：2019

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Radiobiological characterisation of a 28âMeV proton beam delivered by the MC-40 cyclotron.

MC-40 回旋加速器产生的 28MeV 质子束的放射生物学特性

Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia

自噬是轻度缺氧条件下头颈部鳞状细胞癌（HNSCC）细胞放射抗性的主要驱动因素。

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

PARP抑制剂增强头颈部鳞状细胞癌3D球体放射敏感性的有效性

MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance

MEK1/2 抑制剂停药可逆转由 BRAFV600E 扩增驱动的获得性耐药性，而 KRASG13D 扩增则促进 EMT 化学耐药性

Radiobiological characterisation of a 28âMeV proton beam delivered by the MC-40 cyclotron.

MC-40 回旋加速器产生的 28MeV 质子束的放射生物学特性

Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia

自噬是轻度缺氧条件下头颈部鳞状细胞癌（HNSCC）细胞放射抗性的主要驱动因素。

Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma

PARP抑制剂增强头颈部鳞状细胞癌3D球体放射敏感性的有效性

MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance

MEK1/2 抑制剂停药可逆转由 BRAFV600E 扩增驱动的获得性耐药性，而 KRASG13D 扩增则促进 EMT 化学耐药性

Radiobiological characterisation of a 28âMeV proton beam delivered by the MC-40 cyclotron.