日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Generation and Treatment of a Novel Severe Model of Visceral Gaucher Disease by Genetic Therapy.

利用基因疗法构建和治疗新型严重内脏戈谢病模型

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics17050650
Geard Amy F, Massaro Giulia, Hughes Michael P, Arbuthnot Patrick, Waddington Simon N, Rahim Ahad A
发表日期：2025
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Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation

hnRNPA2低复杂度结构域D290V突变体的冷冻电镜结构揭示了D290V如何影响相分离和聚集。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2023.105531
Lu, Jiahui; Ge, Peng; Sawaya, Michael R; Hughes, Michael P; Boyer, David R; Cao, Qin; Abskharon, Romany; Cascio, Duilio; Tayeb-Fligelman, Einav; Eisenberg, David S
相分离
发表日期：2024
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Bioinformatic identification of previously unrecognized amyloidogenic proteins

利用生物信息学方法鉴定先前未被识别的淀粉样蛋白

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2022.101920
Rosenberg, Gregory M; Murray, Kevin A; Salwinski, Lukasz; Hughes, Michael P; Abskharon, Romany; Eisenberg, David S
发表日期：2022
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The expanding amyloid family: Structure, stability, function, and pathogenesis

不断扩大的淀粉样蛋白家族：结构、稳定性、功能和致病机制

期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2021.08.013
Sawaya, Michael R; Hughes, Michael P; Rodriguez, Jose A; Riek, Roland; Eisenberg, David S
发表日期：2021
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Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils

淀粉样原纤维中低复杂度、淀粉样蛋白样、可逆、扭曲片段结构基序的普遍性和物种分布

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2021.101194
Hughes, Michael P; Goldschmidt, Lukasz; Eisenberg, David S
发表日期：2021
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CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

hnRNPA2低复杂度结构域的冷冻电镜结构及其向致病性淀粉样蛋白的转化

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-020-17905-y
Lu, Jiahui; Cao, Qin; Hughes, Michael P; Sawaya, Michael R; Boyer, David R; Cascio, Duilio; Eisenberg, David S
发表日期：2020
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Author Correction: Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation

作者更正：TDP-43 LCD片段的原子结构及其对可逆或致病性聚集的见解

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-019-0316-9
Guenther, Elizabeth L; Cao, Qin; Trinh, Hamilton; Lu, Jiahui; Sawaya, Michael R; Cascio, Duilio; Boyer, David R; Rodriguez, Jose A; Hughes, Michael P; Eisenberg, David S
发表日期：2019
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Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

低复杂度蛋白质片段的原子结构揭示了构成网络结构的扭曲β折叠片层。

期刊:Science
影响因子:45.8
doi:10.1126/science.aan6398
Hughes, Michael P; Sawaya, Michael R; Boyer, David R; Goldschmidt, Lukasz; Rodriguez, Jose A; Cascio, Duilio; Chong, Lisa; Gonen, Tamir; Eisenberg, David S
发表日期：2018
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Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.

TDP-43 LCD片段的原子结构及对可逆或致病性聚集的见解

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-018-0064-2
Guenther Elizabeth L, Cao Qin, Trinh Hamilton, Lu Jiahui, Sawaya Michael R, Cascio Duilio, Boyer David R, Rodriguez Jose A, Hughes Michael P, Eisenberg David S
其它
发表日期：2018
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Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations

SOD1螺旋结构域的原子结构揭示了其不同的寡聚体构象。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.3391
Sangwan, Smriti; Sawaya, Michael R; Murray, Kevin A; Hughes, Michael P; Eisenberg, David S
SOD1
发表日期：2018
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