日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Large-scale human myeloma cell line small molecule compound screen dataset

大规模人类骨髓瘤细胞系小分子化合物筛选数据集

Hughitt, V Keith; Simmons, John K; Gorjifard, Sayeh; Michalowski, Aleksandra; Wilson, Kelli; Zhang, Xiaohu; Shinn, Paul; Klumpp-Thomas, Carleen; McKnight, Crystal; Itkin, Zina; Chen, Lu; Michael, Sam; Keats, Jonathan; Thomas, Craig; Mock, Beverly A

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins

一种基于结构设计的小分子能够消耗 hRpn13Pru 和特定 KEN 盒蛋白。

Xiuxiu Lu,Monika Chandravanshi,Venkata R Sabbasani,Snehal Gaikwad,V Keith Hughitt,Nana Gyabaah-Kessie,Bradley T Scroggins,Sudipto Das,Wazo Myint,Michelle E Clapp,Charles D Schwieters,Marzena A Dyba,Derek L Bolhuis,Janusz W Koscielniak,Thorkell Andresson,Michael J Emanuele,Nicholas G Brown,Hiroshi Matsuo,Raj Chari,Deborah E Citrin,Beverly A Mock,Rolf E Swenson,Kylie J Walters

Drug combinations identified by high-throughput screening promote cell cycle transition and upregulate Smad pathways in myeloma

高通量筛选发现的药物组合可促进骨髓瘤细胞周期转换并上调Smad通路。

Peat, Tyler J; Gaikwad, Snehal M; Dubois, Wendy; Gyabaah-Kessie, Nana; Zhang, Shuling; Gorjifard, Sayeh; Phyo, Zaw; Andres, Megan; Hughitt, V Keith; Simpson, R Mark; Miller, Margaret A; Girvin, Andrew T; Taylor, Andrew; Williams, Daniel; D'Antonio, Nelson; Zhang, Yong; Rajagopalan, Adhithi; Flietner, Evan; Wilson, Kelli; Zhang, Xiaohu; Shinn, Paul; Klumpp-Thomas, Carleen; McKnight, Crystal; Itkin, Zina; Chen, Lu; Kazandijian, Dickran; Zhang, Jing; Michalowski, Aleksandra M; Simmons, John K; Keats, Jonathan; Thomas, Craig J; Mock, Beverly A

mTOR inhibition overcomes RSK3-mediated resistance to BET inhibitors in small cell lung cancer

mTOR 抑制可克服小细胞肺癌中 RSK3 介导的对 BET 抑制剂的耐药性

Anju Kumari, Lisa Gesumaria, Yan-Jin Liu, V Keith Hughitt, Xiaohu Zhang, Michele Ceribelli, Kelli M Wilson, Carleen Klumpp-Thomas, Lu Chen, Crystal McKnight, Zina Itkin, Craig J Thomas, Beverly A Mock, David S Schrump, Haobin Chen

Immune Complex-Driven Generation of Human Macrophages with Anti-Inflammatory and Growth-Promoting Activity

免疫复合物驱动具有抗炎和促进生长活性的人类巨噬细胞的产生

Elizabeth Dalby, Stephen M Christensen, Jingya Wang, Kajal Hamidzadeh, Prabha Chandrasekaran, V Keith Hughitt, Wagner Luiz Tafuri, Rosa Maria Esteves Arantes, Ismael Alves Rodrigues, Ronald Herbst, Najib M El-Sayed, Gary P Sims, David M Mosser

Mycobacterium tuberculosis Inhibits Autocrine Type I IFN Signaling to Increase Intracellular Survival

结核分枝杆菌抑制自分泌I型干扰素信号传导以提高细胞内存活率

Dallas A Banks ,Sarah E Ahlbrand ,V Keith Hughitt ,Swati Shah ,Katrin D Mayer-Barber ,Stefanie N Vogel ,Najib M El-Sayed ,Volker Briken

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis

细胞壁脂质PDIM促进结核分枝杆菌的吞噬体逃逸和宿主细胞排出

Quigley, Jeff; Hughitt, V Keith; Velikovsky, Carlos A; Mariuzza, Roy A; El-Sayed, Najib M; Briken, Volker

The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly Vector

利什曼原虫在其天然白蛉媒介中发育阶段的转录组

Inbar, Ehud; Hughitt, V Keith; Dillon, Laura A L; Ghosh, Kashinath; El-Sayed, Najib M; Sacks, David L

Correction: Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

更正:人-巴西利什曼原虫皮肤病变的宏转录组分析

Christensen, Stephen M; Dillon, Laura A L; Carvalho, Lucas P; Passos, Sara; Novais, Fernanda O; Hughitt, V Keith; Beiting, Daniel P; Carvalho, Edgar M; Scott, Phillip; El-Sayed, Najib M; Mosser, David M

Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion

人-巴西利什曼原虫皮肤病变的宏转录组分析

Christensen, Stephen M; Dillon, Laura A L; Carvalho, Lucas P; Passos, Sara; Novais, Fernanda O; Hughitt, V Keith; Beiting, Daniel P; Carvalho, Edgar M; Scott, Phillip; El-Sayed, Najib M; Mosser, David M