日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cell type-specific control of cardiometabolic disease by the dileucine motif of the LDL receptor-related protein LRP1

LDL受体相关蛋白LRP1的二亮氨酸基序对心血管代谢疾病具有细胞类型特异性调控作用

Igel, Emily; Jaeschke, Anja; Haller, April; Asman, Melissa; Mattam, Ushodaya; Alagarsamy, Jeyashree; Chella Krishnan, Karthickeyan; Hui, David Y

Antimicrobial therapy combined with C-C chemokine receptor type 2 modulation dampens mycobacteria-aggravated monocyte activation and atherosclerosis

抗菌疗法联合CC趋化因子受体2型调节可抑制分枝杆菌加剧的单核细胞活化和动脉粥样硬化。

Egoavil-Espejo, Rocio; Haller, April; Feria, Manuel G; Jain, Sanjay K; Singh, Medha; Zhang, Bin; Qualls, Joseph E; Hui, David Y; Huaman, Moises A

The human glucocorticoid receptor variant rs6190 increases blood cholesterol and promotes atherosclerosis.

人类糖皮质激素受体变异体rs6190会增加血液胆固醇并促进动脉粥样硬化

Durumutla Hima Bindu, Haller April, Noble Greta, Prabakaran Ashok Daniel, McFarland Kevin, Latimer Hannah, Rajput Akanksha, Akinborewa Olukunle, Namjou-Khales Bahram, Hui David Y, Quattrocelli Mattia

ApoE Receptor-2 R952Q Variant in Macrophages Elevates Soluble LRP1 to Potentiate Hyperlipidemia and Accelerate Atherosclerosis in Mice.

巨噬细胞中的 ApoE 受体-2 R952Q 变体可提高可溶性 LRP1 水平,从而增强小鼠高脂血症并加速动脉粥样硬化

Turkson Vanessa, Haller April, Jaeschke Anja, Hui David Y

Distinct Roles of apoE Receptor-2 Cytoplasmic Domain Splice Variants in Cardiometabolic Disease Modulation

apoE受体-2胞质结构域剪接变体在心血管代谢疾病调节中的不同作用

Jaeschke, Anja; Haller, April; Hui, David Y

Receptor-independent fluid-phase macropinocytosis promotes arterial foam cell formation and atherosclerosis

受体非依赖性液相巨胞饮作用促进动脉泡沫细胞形成和动脉粥样硬化

Lin, Hui-Ping; Singla, Bhupesh; Ahn, WonMo; Ghoshal, Pushpankur; Blahove, Maria; Cherian-Shaw, Mary; Chen, Alex; Haller, April; Hui, David Y; Dong, Kunzhe; Zhou, Jiliang; White, Joseph; Stranahan, Alexis M; Jasztal, Agnieszka; Lucas, Rudolf; Stansfield, Brian K; Fulton, David; Chlopicki, Stefan; Csányi, Gábor

Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases

载脂蛋白E在心血管代谢和神经系统健康与疾病中的作用

Alagarsamy, Jeyashree; Jaeschke, Anja; Hui, David Y

Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

在抗磷脂综合征小鼠模型中,滋养层细胞中ApoER2介导的蛋白磷酸酶2A激活可导致先兆子痫。

Chu, Haiyan; Sacharidou, Anastasia; Nguyen, An; Li, Chun; Chambliss, Ken L; Salmon, Jane E; Shen, Yu-Min; Lo, Julie; Leone, Gustavo W; Herz, Joachim; Hui, David Y; Marciano, Denise K; Abrahams, Vikki M; Natale, Bryony V; Montalbano, Alina P; Xiao, Xue; Xu, Lin; Natale, David R; Shaul, Philip W; Mineo, Chieko

Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation

LRP1远端NPxY基序的突变可减轻膳食胆固醇诱导的血脂异常和组织炎症。

Jaeschke, Anja; Haller, April; Cash, James G; Nam, Christopher; Igel, Emily; Roebroek, Anton J M; Hui, David Y

Distinct Influence of Hypercaloric Diets Predominant with Fat or Fat and Sucrose on Adipose Tissue and Liver Inflammation in Mice

高热量饮食(以脂肪或脂肪和蔗糖为主)对小鼠脂肪组织和肝脏炎症的显著影响

Fonseca, Caíque S M; Basford, Joshua E; Kuhel, David G; Konaniah, Eddy S; Cash, James G; Lima, Vera L M; Hui, David Y