日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer

AKT 磷酸化作为小细胞肺癌中 PI3K/mTOR 双重抑制诱导的 mTOR 伴随蛋白的蛋白酶解的预测生物标志物

期刊:Cell and Bioscience
影响因子:6.1
doi:10.1186/s13578-022-00862-y
Ming-Chun Hung #, Wan-Ping Wang #, Ya-Hui Chi
信号转导
肿瘤
表观遗传
肺癌
其它细胞
WB
PI3K/Akt
mTOR
发表日期：2022
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Elevated phthalate exposure and metabolic susceptibility increased breast cancer risk: A 20-y follow-up study in Taiwan

邻苯二甲酸酯暴露量升高和代谢易感性增加乳腺癌风险：一项在台湾进行的20年随访研究

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2507008123
Chen, Hui-Chi; You, San-Lin; Lin, Ching-Hung; Sun, Chien-Wen; Chiang, Chun-Ju; Yang, Hwai-I; Wang, Li-Yu; Sun, Chien-An; Liu, Jessica; Jen, Chin-Lan; Chen, Yuh-An; Lu, Yen-Shen; Cheng, Ann-Lii; Wang, Shu-Li; Hsiung, Chao A; Chen, Chien-Jen
肿瘤
乳腺癌
肿瘤免疫
代谢
发表日期：2026
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Baseline plasma p-tau217/Aβ42 as a sensitive marker for the severity of Alzheimer's disease continuum

基线血浆p-tau217/Aβ42作为阿尔茨海默病连续谱严重程度的敏感标志物

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-026-07939-z
Liu, Wen-Zheng; Xue, Mei; Sheng, Ze-Hu; Wei, Yu-Qian; Ma, Ya-Hui; Li, Jie-Qiong; Song, Jing-Hui; Chi, Song; Ou, Ya-Nan
阿尔茨海默症
发表日期：2026
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Tissue-specific distribution of cytotoxic triterpene saponins in three Red Sea sea cucumbers

红海三种海参中细胞毒性三萜皂苷的组织特异性分布

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-39441-3
Fayez, Shaimaa; Abed, Karim; Moussa, Mostafa S; Zohdy, Mennatallah N; Ali, Amira M; El-Gohary, Miral A; Awaad, Mennatallah M; Alshawarby, Noura M; Sedky, Rana I; Taha, Myar E; El-Sayed, Toqa H; Abd Elhamied, Esraa M; Mahmoud, Nouran G; Serafeem, Trivina E; Chen, Po-Jen; Huang, Hui-Chi; Chen, Lo-Yun; Lai, Kuei-Hung; El-Shazly, Mohamed
细胞生物学
毒理研究
发表日期：2026
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Manifold-guided SMOTified dual-channel conditional GAN improving highly-imbalanced biomedical data classification

基于流形引导的SMOT化双通道条件GAN改进了高度不平衡的生物医学数据分类

期刊:Discover Oncology
影响因子:2.9
doi:10.1007/s12672-026-04721-x
Lin, Liang-Sian; Lin, Chien-Hsin; Chang, Hsin-Yu; Chuang, Hui-Chi; Liu, Chih-Ching
GAN
SMO
发表日期：2026
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HBO1 functions as an epigenetic barrier to hepatocyte plasticity and reprogramming during liver injury

HBO1在肝损伤期间发挥表观遗传屏障的作用，阻碍肝细胞的可塑性和重编程。

期刊:Cell Stem Cell
影响因子:19.8
doi:10.1016/j.stem.2025.04.010
Wei-Chien Yuan ，Andrew S Earl ，Sai Ma ，Karel Alcedo ，Jacquelyn O Russell ，Fabiana M Duarte ，Yen-Ting Chu ，Pei-Chi Chang ，Hsin-Yi Chen ，Hsin-Hui Chi ，Qian Zhu ，Alejo E Rodriguez-Fraticelli ，Sachin H Patel ，Yu-Ru Lee ，Jason D Buenrostro ，Fernando D Camargo
表观遗传
肝损伤
发表日期：2025
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PTEN regulates vagal-insulin signaling to optimize autonomic output determining peripheral inflammatory and metabolic homeostasis.

PTEN 调节迷走神经-胰岛素信号传导，以优化自主神经输出，从而决定外周炎症和代谢稳态。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67192-8
Li Yu Zhe, Son Joe Eun, Vo Nathaniel, Bellisimo Catherine, Lee Ju Hee, Rapps Joshua, Pollock-Tahiri Evan, Ghebreselassie Martha, Chen Chuck T, Bazinet Richard P, Billia Filio, Suzuki Akira, Hui Chi-Chung, Mak Tak W, Sung Hoon-Ki, Yoo Paul, Woo Minna
神经科学
PTEN
炎症
发表日期：2025
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Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights

溶瘤病毒OH2延长了PD-1预处理黑色素瘤患者的生存期：Ia/Ib期试验结果和生物标志物见解

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010662
Wang, Xuan; Tian, Hui; Chi, Zhihong; Si, Lu; Sheng, Xinan; Hu, Han; Gu, Xiangyong; Li, Siming; Li, Caili; Lian, Bin; Zhou, Li; Mao, Lili; Tang, Bixia; Yan, Xieqiao; Wei, Xiaoting; Li, Juan; Liu, Binlei; Guo, Jun; Kong, Yan; Cui, Chuanliang
微生物学
黑色素瘤
PD-1
发表日期：2025
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The kinesin-4 protein KIF27 forms a cytoskeletal scaffold at the transition zone to promote motile cilia structural integrity

驱动蛋白-4 KIF27 在过渡区形成细胞骨架支架，以促进运动纤毛的结构完整性。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2515392122
Park, Hyunji; Choi, Minjun; Zhang, Yu; Cheung, Helen Oi-Lam; Makino, Shigeru; Yoshikawa, Yoshiaki; Qi, Haoran; Liu, Zheng; Lan, Guocheng; Fu, Guoling; Wang, Qian; Guo, Shiny Shengzhen; Liu, Pengtao; Liu, Zhen; Ti, Shih-Chieh; Wang, Won-Jing; Li, Xiang David; Ni, Tao; Hui, Chi-Chung; He, Mu
细胞生物学
发表日期：2025
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Orally Bioavailable and Site-Selective Covalent STING Inhibitor Derived from a Macrocyclic Marine Diterpenoid

一种源自大环海洋二萜类化合物的口服生物利用度高且具有位点选择性的共价STING抑制剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c02665
Guang-Hao Niu ,Wan-Chi Hsiao ,Po-Hsun Lee ,Li-Guo Zheng ,Yu-Shao Yang ,Wei-Cheng Huang ,Chih-Chien Hsieh ,Tai-Yu Chiu ,Jing-Ya Wang ,Ching-Ping Chen ,Chen-Lung Huang ,May-Su You ,Yi-Ping Kuo ,Chien-Ming Wang ,Zhi-Hong Wen ,Guann-Yi Yu ,Chiung-Tong Chen ,Ya-Hui Chi ,Chun-Wei Tung ,Shu-Ching Hsu ,Teng-Kuang Yeh ,Ping-Jyun Sung ,Mingzi M Zhang ,Lun Kelvin Tsou
STING
发表日期：2025
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