A novel immunocompetent transgenic mouse model of DHF reveals Syk-mediated Th2-polarized cytokine storm as a key driver of vascular leakage
一种新型的具有免疫功能的转基因小鼠登革出血热模型揭示了Syk介导的Th2极化细胞因子风暴是血管渗漏的关键驱动因素。
期刊:Emerging Microbes & Infections
影响因子:8.4
doi:10.1080/22221751.2025.2531178
YuYa Wang,Wei Yang,YuanSong Yang,HuiHui Cheng,Rui Xiong,Xi Wu,Nan Xu,ShuNan Liu,Zhe Qu,Chen Ling,Yuan Cao,Yanwei Yang,HaoYang Zhao,WenDa Gu,Yong Wu,SuSu Liu,Yining Wang,Yu Wang,SanLong Wang,Rui Fu,WeiJin Huang,Hongning Zhou,Wei Wei,Jing An,YouChun Wang,ChangFa Fan
出血热
Mouse
细胞生物学
免疫/内分泌
T细胞
SYK
T细胞
