日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Multimodal artificial intelligence predicts PIK3CA mutation in breast cancer from digital pathology and clinical data: a multicenter study

多模态人工智能利用数字病理和临床数据预测乳腺癌中PIK3CA突变：一项多中心研究

期刊:Cancer Biology & Medicine
影响因子:8.4
doi:10.20892/j.issn.2095-3941.2025.0771
Miao, Jiaxian; Liu, Qi; Zhao, Jianing; Fan, Shishun; Wang, Shenwen; Ye, Feng; Wu, Si; Li, Jinze; Zhang, Huirui; Zhang, Meng; Bu, Hong; Han, Xiao; Teng, Lianghong; Liu, Yueping
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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A platelet-rich plasma-loaded chitosan-based hydrogel for promoting type 2 diabetes wound healing.

一种载有富血小板血浆的壳聚糖基水凝胶，用于促进2型糖尿病伤口愈合。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2026.115162
Wang Na, Zhu Huirui, Li Dongkun, Wang Xuena, Zhang Ziyan, Chai Bao, Li Meining, Gong Tao
血小板
糖尿病
代谢
发表日期：2026
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DNA Hypermethylation of the ZNF382 Promoter Region and Low mRNA Expression of ZNF382 Promote Diffuse Large B-Cell Lymphoma Occurrence and Progression.

ZNF382启动子区域的DNA高甲基化和ZNF382的低mRNA表达促进弥漫性大B细胞淋巴瘤的发生和发展。

期刊:Cancer Reports
影响因子:1.9
doi:10.1002/cnr2.70502
An Wanhua, Guo Shuli, Liu Sizhe, Xiao Pengli, Mi Emma, Wang Huirui
淋巴瘤
细胞生物学
B细胞
发表日期：2026
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Interaction between CDC6 and Tmod3 accelerates resistance to paclitaxel through focal adhesion assembly.

CDC6 和 Tmod3 之间的相互作用通过粘着斑组装加速对紫杉醇的耐药性。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02490-7
Liu Yue, Wang Huirui, Zhan Jie, Sun Jiabo, Sun Yan, Fu Xiaojie, Lv Dongxue, Li Xiuyun, Dong Ting, Lou Hongxiang
CDC6
发表日期：2025
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Stress granule clearance mediated by V-ATPase-interacting protein NCOA7 mitigates ovarian aging.

V-ATPase 相互作用蛋白 NCOA7 介导的应激颗粒清除可减轻卵巢衰老

期刊:Nature Aging
影响因子:19.4
doi:10.1038/s43587-025-00927-w
Dong Ting, Li Nianyu, Wang Huirui, Zhu Hanbing, Gao Yinghui, Liu Yue, Fang Fang, Fu Xiaojie, Si Pinxin, Li Cheng, Li Mei, Wang Fei, Zhao Shidou, Guo Ting, Cui Linlin, Jiang Xinyi, Liu Xiaohui, Zhao Han, Qin Yingying, Chen Zi-Jiang, Lou Hongxiang, Jiao Xue
其它
细胞衰老
发表日期：2025
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Baicalin affects the progression of diabetic retinopathy through the RAGE/PXDN/PI3K/AKT pathway.

黄芩苷通过 RAGE/PXDN/PI3K/AKT 通路影响糖尿病视网膜病变的进展。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-07590-0
Gao Yi, Liu Huirui, Yang Tao, Wang Jianwen
糖尿病视网膜病变
信号转导
视网膜病变
神经科学
代谢
RAGE
糖尿病
AKT
发表日期：2025
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SIRT1 Prevents Lens Epithelial Cell Senescence During Age-Related Cataract via Regulating p66Shc.

SIRT1 通过调节 p66Shc 防止年龄相关性白内障期间晶状体上皮细胞衰老

期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.70155
Liu Huirui, Sun Liyao, Mi Yu, Gao Yi, Luo Jialin, Kang Fengchun, Bai Yujing, Yu Xiaohan, Ge Hongyan
细胞生物学
Senescence
细胞衰老
发表日期：2025
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HCDT 2.0: A Highly Confident Drug-Target Database for Experimentally Validated Genes, RNAs, and Pathways

HCDT 2.0：一个高度可靠的药物靶点数据库，包含经实验验证的基因、RNA和通路

期刊:Scientific Data
影响因子:6.9
doi:10.1038/s41597-025-04981-2
Liu, Xinying; Feng, Dehua; Chen, Jiaqi; Li, Tianyi; Wang, Xuefeng; Zhang, Ruijie; Chen, Jian; Cai, Xingjun; Han, Huirui; Yu, Lei; Li, Xia; Li, Bing; Wang, Limei; Li, Jin
信号转导
发表日期：2025
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Prediction of Moderate-to-Severe Sepsis-Associated Acute Kidney Injury Using a Dual-Timepoint Machine Learning Model: Development, Multiregional Validation, and Clinical Deployment Study

利用双时间点机器学习模型预测中重度脓毒症相关急性肾损伤：模型开发、多区域验证和临床应用研究

期刊:Journal of Medical Internet Research
影响因子:6
doi:10.2196/73840
Ge, Xinbo; Chen, Weiwei; Shi, Jianshan; Zhang, Jiaqiang; Tai, Hao; Zhang, Ying; Wang, Biao; Liu, Wei; Chen, Song; Han, Huirui
炎症/感染
败血症
毒理研究
肾损伤
发表日期：2025
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Drug discovery for chemotherapeutic resistance based on pathway-responsive gene sets and its application in breast cancer

基于通路响应基因集的化疗耐药药物发现及其在乳腺癌中的应用

期刊:Frontiers in Bioinformatics
影响因子:3.9
doi:10.3389/fbinf.2025.1661601
Feng, Dehua; Hao, Jingwen; Li, Lingxu; Chen, Jian; Liu, Xinying; Zhang, Ruijie; Han, Huirui; Li, Tianyi; Wang, Xuefeng; Li, Xia; Yu, Lei; Li, Bing; Li, Jin; Wang, Limei
信号转导
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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