日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Sustained Benefit of Blinatumomab in Infants With KMT2A-Rearranged ALL: Long-Term Outcomes, Toxicity, and Pharmacokinetics

Blinatumomab 对 KMT2A 重排 ALL 患儿的持续疗效：长期结果、毒性和药代动力学

期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO-25-01806
Vieira Martins, Miguel; de Lorenzo, Paola; Kotecha, Rishi S; Attarbaschi, Andishe; Escherich, Gabriele; Nysom, Karsten; Stary, Jan; Ferster, Alina; Brethon, Benoit; Locatelli, Franco; Schrappe, Martin; Scholte-van Houtem, Peggy E; Valsecchi, Maria G; Huitema, Alwin D R; Pieters, Rob; van der Sluis, Inge M
KMT2A
毒理研究
发表日期：2026
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KRAS G12C inhibitors versus chemotherapy in second line and beyond in adults with advanced or metastatic non-small cell lung cancer (NSCLC) harbouring the KRAS G12C mutation

KRAS G12C 抑制剂与化疗在二线及后续治疗中对携带 KRAS G12C 突变的晚期或转移性非小细胞肺癌 (NSCLC) 成人患者的疗效比较

期刊:Cochrane Database of Systematic Reviews
影响因子:9.4
doi:10.1002/14651858.CD016054
Noordhof, Anneloes; Asmara, Oke Dimas; de Jong, Kim; Gijtenbeek, Rolof Gp; Huitema, Ymkje Ma; van Vollenhoven, Femke Hm; Venmans, Ben Jw; Hendriks, Lizza; van Geffen, Wouter H
肺癌
肿瘤
肿瘤免疫
CLC
细胞生物学
RAS
发表日期：2026
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Fludarabine dosing in the youngest children: safety first

氟达拉滨在婴幼儿中的用药：安全第一

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2025018108
Admiraal, Rick; Barnett, Shelby; Lindemans, Caroline A; Huitema, Alwin D R; Veal, Gareth J
发表日期：2026
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Reducing the Burden of Interaction Studies in Cancer Patients Using a Stable Isotopically Labeled Microtracer: A Proof-of-Concept Study with Alectinib

利用稳定同位素标记微示踪剂减轻癌症患者相互作用研究的负担：阿来替尼概念验证研究

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70141
Mohmaed Ali, Ma Ida; van der Heijden, Lisa T; Tibben, Matthijs; Rosing, Hilde; Kalicharan, Raween; Ruiter, Gerrina; Beijnen, Jos H; Huisman-Siebinga, Hinke; Huitema, Alwin D R; Steeghs, Neeltje
肿瘤
肿瘤免疫
发表日期：2026
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Bidirectional Interaction Between Liposomal Amphotericin B Pharmacokinetics and Parasite Dynamics in Patients With Post-Kala-Azar Dermal Leishmaniasis: Potential Implications for Optimal Dosing

脂质体两性霉素B药代动力学与黑热病后皮肤利什曼病患者寄生虫动力学之间的双向相互作用：对最佳剂量方案的潜在影响

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70124
Chu, Wan-Yu; Singh, Om Prakash; Sundar, Shyam; Mondal, Dinesh; Pandey, Krishna; Das, Pradeep; Roseboom, Ignace C; Raja, Sheeraz; Torres, Ana; Carrillo, Eugenia; Huitema, Alwin D R; Alves, Fabiana; Dorlo, Thomas P C
微生物学
发表日期：2026
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Population Pharmacokinetics of Total and Protein-Unbound Prednisolone in Children with Immune-Mediated and Systemic Inflammatory Diseases

免疫介导和全身性炎症性疾病患儿体内总泼尼松龙和蛋白游离泼尼松龙的群体药代动力学

期刊:Clinical Pharmacokinetics
影响因子:4
doi:10.1007/s40262-025-01601-5
Möhlmann, Julia E; Lindemans, Caroline A; Jansen, Marc H A; van Luin, Matthijs; Punt, Arjen M; Ezzafzafi, Solaiman; Nierkens, Stefan; Huitema, Alwin D R; de Vries Schultink, Aurelia H M
炎症/感染
炎症
免疫/内分泌
发表日期：2026
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Semi-Physiological Population Pharmacokinetic Modeling of Oral and Intravenous Paracetamol to Quantify Presystemic Metabolism and Enterohepatic Recirculation

口服和静脉注射对乙酰氨基酚的半生理群体药代动力学模型，用于量化首过代谢和肠肝循环

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70168
Lau, Cedric; van Kesteren, Charlotte; Smeenk, Robert M; Beex-Oosterhuis, Marieke M; Koch, Birgit C P; Chan, Lingtak-Neander; Lin, Yvonne S; van Rongen, Anne; Knibbe, Catherijne A J; Huitema, Alwin D R; Huisman-Siebinga, Hinke
代谢
发表日期：2026
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Analytical Validation of an Annotation Tool for WGS-Based Pharmacogenomics: Preparing for Clinical Implementation in Pediatric Oncology

基于全基因组测序的药物基因组学注释工具的分析验证：为在儿科肿瘤学中的临床应用做准备

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70540
Diekstra, Meta H M; Biesot, Nienke; Donders, Julie; Verwiel, Eugène T P; Janse, Alex; Huitema, Alwin D R; Hanff, Lidwien M; Tops, Bastiaan B J; Kemmeren, Patrick; Hehir-Kwa, Jayne Y
肿瘤
肿瘤免疫
发表日期：2026
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An Overview of Liquid Chromatography-Mass Spectrometry (LC-MS) Methods for the Quantification of Antibody-Drug Conjugates

液相色谱-质谱联用（LC-MS）方法在抗体-药物偶联物定量分析中的应用概述

期刊:Biomedical Chromatography
影响因子:1.7
doi:10.1002/bmc.70334
Buitelaar, Pauline L M; Rosing, Hilde; Beijnen, Jos H; Steeghs, Neeltje; Huitema, Alwin D R
多发性硬化症
发表日期：2026
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NICHD Magnetic Resonance Brain Imaging Score in Term Infants With Hypoxic-Ischemic Encephalopathy: A Secondary Analysis of a Randomized Clinical Trial

NICHD磁共振脑成像评分在足月缺氧缺血性脑病婴儿中的应用：一项随机临床试验的二次分析

期刊:Jama Pediatrics
影响因子:18
doi:10.1001/jamapediatrics.2024.6209
Shankaran, Seetha; Laptook, Abbot R; Guimaraes, Carolina; Murnick, Johnathan; McDonald, Scott A; Das, Abhik; Petrie Huitema, Carolyn M; Pappas, Athina; Higgins, Rosemary D; Hintz, Susan R; Zaterka-Baxter, Kristin M; Van Meurs, Krisa P; Sokol, Gregory M; Chalak, Lina F; Colaizy, Tarah T; Devaskar, Uday; Tyson, Jon E; Reynolds, Anne Marie; DeMauro, Sara B; Sánchez, Pablo J; Laughon, Matthew M; Carlo, Waldemar A; Watterberg, Kristi; Puopolo, Karen M; Hibbs, Anna Maria; Hamrick, Shannon E G; Cotten, C Michael; Barks, John; Poindexter, Brenda B; Truog, William E; D'Angio, Carl T
神经科学
发表日期：2025
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