Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism
GSK343 体外抑制曼氏血吸虫的组蛋白甲基转移酶 EZH2 可减少产卵量并降低与 DNA 复制和非编码 RNA 代谢有关的基因表达
期刊:PLoS Neglected Tropical Diseases
影响因子:
doi:10.1371/journal.pntd.0006873
Adriana S A Pereira, Murilo S Amaral, Elton J R Vasconcelos, David S Pires, Huma Asif, Lucas F daSilva, David A Morales-Vicente, Vitor C Carneiro, Claudia B Angeli, Giuseppe Palmisano, Marcelo R Fantappie, Raymond J Pierce, João C Setubal, Sergio Verjovski-Almeida
