日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of CFIm activates YAP/TAZ and connects mRNA cleavage and polyadenylation inhibition to BRCAness.

CFIm 的缺失激活 YAP/TAZ,并将 mRNA 切割和多聚腺苷酸化抑制与 BRCA 基因突变联系起来。

Goldthorpe Madeleine, Hou Jiahui, Nadendla Abhi, Osmanbeyoglu Hatice Ulku, Hwang Hun-Way

An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus

mRNA 加工途径通过控制细胞核中的翻译控制来抑制转移

Albertas Navickas #, Hosseinali Asgharian #, Juliane Winkler, Lisa Fish, Kristle Garcia, Daniel Markett, Martin Dodel, Bruce Culbertson, Sohit Miglani, Tanvi Joshi, Keyi Yin, Phi Nguyen, Steven Zhang, Nicholas Stevers, Hun-Way Hwang, Faraz Mardakheh, Andrei Goga, Hani Goodarzi

A twin UGUA motif directs the balance between gene isoforms through CFIm and the mTORC1 signaling pathway

双 UGUA 基序通过 CFIm 和 mTORC1 信号通路调控基因亚型之间的平衡

R Samuel Herron ,Alexander K Kunisky ,Jessica R Madden ,Vivian I Anyaeche ,May Z Maung ,Hun-Way Hwang

Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

DNA损伤后MSL1选择性多聚腺苷酸化的改变可保护癌细胞免受化疗药物诱导的细胞凋亡

Alexander K Kunisky ,Vivian I Anyaeche ,R Samuel Herron ,Christopher Y Park ,Hun-Way Hwang

Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types

特定转录本的差异性3'端加工扩展了神经元细胞类型中的调控和蛋白质多样性

Jereb, Saša; Hwang, Hun-Way; Van Otterloo, Eric; Govek, Eve-Ellen; Fak, John J; Yuan, Yuan; Hatten, Mary E; Darnell, Robert B

cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation

cTag-PAPERCLIP揭示了替代性多聚腺苷酸化促进细胞类型特异性蛋白质多样性,并随着小胶质细胞活化而改变Araf亚型

Hun-Way Hwang ,Yuhki Saito ,Christopher Y Park ,Nathalie E Blachère ,Yoko Tajima ,John J Fak ,Ilana Zucker-Scharff ,Robert B Darnell

PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage

PAPERCLIP 识别 MicroRNA 靶标以及 CstF64/64tau 在促进非规范 poly(A) 位点使用中的作用

Hun-Way Hwang, Christopher Y Park, Hani Goodarzi, John J Fak, Aldo Mele, Michael J Moore, Yuhki Saito, Robert B Darnell

Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice

系统性递送scAAV8编码的miR-29a可改善四氯化碳处理小鼠的肝纤维化

Knabel, Matthew K; Ramachandran, Kalyani; Karhadkar, Sunil; Hwang, Hun-Way; Creamer, Tyler J; Chivukula, Raghu R; Sheikh, Farooq; Clark, K Reed; Torbenson, Michael; Montgomery, Robert A; Cameron, Andrew M; Mendell, Joshua T; Warren, Daniel S

Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A

独特的 microRNA 表达特征与黑色素瘤亚型相关,并受 HIF1A 调控

Hun-Way Hwang, Laura L Baxter, Stacie K Loftus, Julia C Cronin, Niraj S Trivedi, Bhavesh Borate, William J Pavan

Melanocytes don't always take the high road

黑色素细胞并非总是走正道。

Hwang, Hun-Way; Pavan, William J