日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The β(IV)-Spectrin/STAT3 Complex Regulates the Orientation of Cardiac Hypertrophic Growth

β(IV)-Spectrin/STAT3复合物调节心脏肥大生长的方向

Nassal, Drew M; Mohta, Shivangi; Shaheen, Rebecca; Liu, Haiyan; Cavus, Omer; Buck, Benjamin; Lococo, Simon; Winkle, Alexander J; Pyles, Jolie B; Leahy, Nicholas; Xu, Xianyao; Hund, Thomas J

12,13-diHOME protects against the age-related decline in cardiovascular function via attenuation of CaMKII.

12,13-二羟基维生素D3通过减弱CaMKII来防止与年龄相关的心血管功能下降

Nirengi Shinsuke, Buck Benjamin, Das Devleena, Peres Valgas da Silva Carmem, Calyeca Jazmin, Baer Lisa A, Huang Hsiang-Ling, Vidal Pablo, Dewal Revati S, Pinckard Kelsey M, Félix-Soriano Elisa, Hernandez-Saavedra Diego, Gerea Andrew, Dathathreya Kavya, Duarte-Sanmiguel Silvia, Saldana Ty A, Hookfin Harrison L, Gorr Matthew W, Bussberg Valerie, Aristizabal-Henao Juan J, Kiebish Michael A, Middelbeek Roeland J W, Goodyear Laurie J, Coen Paul M, Chinthalapudi Krishna, Wold Loren E, Mora Ana L, Hund Thomas J, Gallego-Perez Daniel, Stanford Kristin I

Distinct intracellular spatiotemporal expression of Calmodulin genes underlies functional diversity of Calmodulin-dependent signalling in cardiac myocytes

心肌细胞中钙调蛋白基因独特的时空表达是钙调蛋白依赖性信号传导功能多样性的基础。

Bogdanov, Vladimir; Mariangelo, Juan I E; Soltisz, Andrew M; Sakuta, Galina; Pokrass, Anastasia; Beard, Casey; Orengo, Benjamin Hernandez; Kalinin, Roman; Ulker, Ali; Yunker, Bennett; Tikunova, Svetlana; Thuma, Jenna; Xu, Xianyao; Hund, Thomas J; Veeraraghavan, Rengasayee; Davis, Jonathan P; Györke, Sandor

Evaluation of Tideglusib as a Disease Modifying Therapy in Murine Models of Arrhythmogenic Cardiomyopathy.

在致心律失常性心肌病小鼠模型中评估 Tideglusib 作为疾病修饰疗法的疗效

Malhotra Nipun, Cavus Omer, Wallace Michael J, Bobik John T, You Kevin, Takenaka Sarah S, Abdallah Danielle, Mohler Eleanor J, Antwi-Boasiako Steve, Murphy Nathaniel P, Sucharski-Argall Holly, Xu Xianyao, Chelko Stephen P, Hund Thomas J, Roberts Jason D, Mohler Peter J, El Refaey Mona

The two-pore K(+) channel TREK-1 regulates pressure overload-induced cardiac remodeling.

双孔K(+)通道TREK-1调节压力超负荷引起的心脏重塑

Johnson Cemantha M L, Nassal Drew M, Winkle Alexander J, Buck Benjamin, Xu Xianyao, Wan Xiaoping, Han Mei, Lococo Simon, Leahy Nicholas, Mohta Shivangi, Shaheen Rebecca, Cavus Omer, Kohli Aaryan, Cao Yuanyuan, El Refaey Mona, Smith Sakima, Ai Xun, Deschênes Isabelle, Hund Thomas J

Advanced 4-chamber echocardiography techniques enable clinically matched precise characterization of heart disease progression in mice

先进的四腔心超声心动图技术能够对小鼠心脏疾病的进展进行与临床相匹配的精确表征。

Kacira, Ege; Oueis, Mariam F; Tamimi, Nawal H; Sturgill, Sarah L; Xu, Xianyao; Hund, Thomas J; Ziolo, Mark T; Han, Yuchi; Deschênes, Isabelle; Fu, Ji-Dong

MicroRNA-1 Deficiency Is a Primary Etiological Factor Disrupting Cardiac Contractility and Electrophysiological Homeostasis

MicroRNA-1缺乏是破坏心肌收缩力和电生理稳态的主要病因

Yang, Dandan; Wan, Xiaoping; Schwieterman, Neill; Cavus, Omer; Kacira, Ege; Xu, Xianyao; Laurita, Kenneth R; Wold, Loren E; Hund, Thomas J; Mohler, Peter J; Deschênes, Isabelle; Fu, Ji-Dong

Cardiac-Specific Deletion of Scn8a Mitigates Dravet Syndrome-Associated Sudden Death in Adults

心脏特异性敲除Scn8a基因可减轻成人Dravet综合征相关猝死

King, D Ryan; Demirtas, Mustafa; Tarasov, Mikhail; Struckman, Heather L; Meng, Xiaolei; Nassal, Drew; Moise, Nicolae; Miller, Alec; Min, Dennison; Soltisz, Andrew M; Anne, Midhun N K; Alves Dias, Patrícia A; Wagnon, Jacy L; Weinberg, Seth H; Hund, Thomas J; Veeraraghavan, Rengasayee; Radwański, Przemysław B

Phosphorylation of cardiac sodium channel at Ser571 anticipates manifestations of the aging myopathy.

心脏钠通道 Ser571 位点的磷酸化预示着衰老性肌病的发生

Pizzo Emanuele, Cervantes Daniel O, Ketkar Harshada, Ripa Valentina, Nassal Drew M, Buck Benjamin, Parambath Sreema P, Di Stefano Valeria, Singh Kanwardeep, Thompson Carl I, Mohler Peter J, Hund Thomas J, Jacobson Jason T, Jain Sudhir, Rota Marcello

PL01.4.A LATE BREAKING ABSTRACT: A LONG PEPTIDE VACCINE TARGETING THE CLONAL DRIVER MUTATION H3K27M IN ADULT PATIENTS WITH DIFFUSE MIDLINE GLIOMA

PL01.4.A 最新摘要:一种靶向弥漫性中线胶质瘤成人患者克隆驱动突变 H3K27M 的长肽疫苗

Yang, Dandan; Wan, Xiaoping; Dennis, Adrienne T; Bektik, Emre; Wang, Zhihua; Costa, Mauricio G S; Fagnen, Charline; Vénien-Bryan, Catherine; Xu, Xianyao; Gratz, Daniel H; Hund, Thomas J; Mohler, Peter J; Laurita, Kenneth R; Deschênes, Isabelle; Fu, Ji-Dong; Grassl, N; Poschke, I; Lindner, K; Kromer, K; Bunse, L; Mildenberger, I; Jaehne, K; Haltenhof, G; Tan, C; Green, E; Kessler, T; Suwala, A; Sahm, F; Eisele, P; Breckwoldt, M; Vajkoczy, P; Grauer, O; Herrlinger, U; Tonn, J; Denk, M; Bendszus, M; von Deimling, A; Winkler, F; Wick, W; Lindner, J; Platten, M; Sahm, K