The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC
强效CD4模拟物对HIV-1 Env的不对称打开作用，使得抗辅助受体结合位点抗体能够介导抗体依赖性细胞毒性作用（ADCC）。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65866-x
Richard, Jonathan; Grunst, Michael W; Niu, Ling; Díaz-Salinas, Marco A; Zhu, Li; Tolbert, William D; Marchitto, Lorie; Zhou, Fei; Bourassa, Catherine; Kim, Hongil; Boodapati, Sri Lakshmi Tejaswi; Yang, Derek; Chiu, Ta Jung; Chen, Hung-Ching; Benlarbi, Mehdi; Beaudoin-Bussières, Guillaume; Gottumukkala, Suneetha; Li, Wenwei; Dionne, Katrina; Bélanger, Étienne; Chatterjee, Debashree; Medjahed, Halima; Hendrickson, Wayne A; Sodroski, Joseph; Lang, Zabrina C; Morton, Abraham J; Huang, Rick K; Matthies, Doreen; Smith, Amos B 3rd; Kumar, Priti; Mothes, Walther; Munro, James B; Pazgier, Marzena; Finzi, Andrés
CD4
细胞生物学
毒理研究
DCC
微生物学
信号转导
T细胞
HIV
