日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them

结核分枝杆菌三功能酶的晶体学片段结合研究表明,其活性位点存在酰基辅酶A底物尾部的结合口袋,并且二者之间可能存在底物通道。

Dalwani, Subhadra; Metz, Alexander; Huschmann, Franziska U; Weiss, Manfred S; Wierenga, Rik K; Venkatesan, Rajaram

Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives

嘌呤和嘧啶核苷酸与人胞外5'-核苷酸酶(CD73)的底物结合模式及其双膦酸衍生物的抑制作用

Scaletti, Emma; Huschmann, Franziska U; Mueller, Uwe; Weiss, Manfred S; Sträter, Norbert

A case-crossover study on the effect of short-term exposure to moderate levels of air pollution on the risk of heart failure

一项关于短期暴露于中等水平空气污染对心力衰竭风险影响的病例交叉研究

Huschmann, Ariane; Rasche, Marius; Schlattmann, Peter; Witte, Otto W; Schwab, Matthias; Schulze, P Christian; Rakers, Florian

Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library

利用新型、多样化且经济实惠的96种化合物片段库,通过晶体学片段筛选获得内皮硫肽酶-片段复合物的结构

Huschmann, Franziska U; Linnik, Janina; Sparta, Karine; Ühlein, Monika; Wang, Xiaojie; Metz, Alexander; Schiebel, Johannes; Heine, Andreas; Klebe, Gerhard; Weiss, Manfred S; Mueller, Uwe

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

单层跨膜细胞色素P450的结构表明,其催化结构域相对于双层膜的方向受到限制。

Monk, Brian C; Tomasiak, Thomas M; Keniya, Mikhail V; Huschmann, Franziska U; Tyndall, Joel D A; O'Connell, Joseph D 3rd; Cannon, Richard D; McDonald, Jeffrey G; Rodriguez, Andrew; Finer-Moore, Janet S; Stroud, Robert M