日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional analysis of bipartite NRF2 activators that overcome feedback regulation for age-related chronic diseases.

对克服与年龄相关的慢性疾病的反馈调节的双元 NRF2 激活剂进行功能分析

Hushpulian Dmitry M, Kaidery Navneet Ammal, Soni Priyanka, Poloznikov Andrey A, Zakhariants Arpenik A, Razumovskaya Alexandra V, Silkina Mariia O, Tishkov Vladimir I, Kazakov Eliot H, Brown Abraham M, Gaisina Irina N, Ahn Young-Hoon, Kazakov Sergey V, Krucher Nancy, Sharma Sudarshana M, Paul Bindu D, Gazaryan Irina G, Nikulin Sergey V, Thomas Bobby

Structure-Functional Examination of Cysteine Synthase A (CysK) from Limosilactobacillus reuteri LR1

对罗伊氏乳杆菌LR1半胱氨酸合成酶A(CysK)的结构-功能研究

Pometun, Anastasia A; Les, Evgenii K; Chernobrovkina, Alla V; Gorbovskaia, Anastasiia V; Chikurova, Natalia Yu; Loginova, Anastasia A; Antipov, Alexey N; Mordkovich, Nadezhda N; Shaposhnikov, Leonid A; Savin, Svyatoslav S; Kleymenov, Sergey Yu; Matyuta, Ilya O; Boyko, Konstantin M; Minyaev, Mikhail E; Hushpulian, Dmitry M; Pometun, Evgenii V; Tishkov, Vladimir I

A critical appraisal of ferroptosis in Alzheimer's and Parkinson's disease: new insights into emerging mechanisms and therapeutic targets

对阿尔茨海默病和帕金森病中铁死亡的批判性评价:对新兴机制和治疗靶点的新见解

Soni, Priyanka; Ammal Kaidery, Navneet; Sharma, Sudarshana M; Gazaryan, Irina; Nikulin, Sergey V; Hushpulian, Dmitry M; Thomas, Bobby

Emerging small molecule inhibitors of Bach1 as therapeutic agents: Rationale, recent advances, and future perspectives

Bach1小分子抑制剂作为治疗药物的新兴应用:理论基础、最新进展及未来展望

Hushpulian, Dmitry M; Kaidery, Navneet Ammal; Dutta, Debashis; Sharma, Sudarshana M; Gazaryan, Irina; Thomas, Bobby

Carotenoids from Starfish Patiria pectinifera: Therapeutic Activity in Models of Inflammatory Diseases

海星(Patiria pectinifera)中的类胡萝卜素:在炎症性疾病模型中的治疗活性

Popov, Aleksandr M; Kozlovskaya, Emma P; Klimovich, Anna A; Rutckova, Tatyana A; Vakhrushev, Aleksey I; Hushpulian, Dmitry M; Gazaryan, Irina G; Makhankov, Vyacheslav V; Son, Oksana M; Tekutyeva, Liudmila A

Bach1 derepression is neuroprotective in a mouse model of Parkinson's disease

Bach1去抑制在帕金森病小鼠模型中具有神经保护作用

Ahuja, Manuj; Ammal Kaidery, Navneet; Attucks, Otis C; McDade, Erin; Hushpulian, Dmitry M; Gaisin, Arsen; Gaisina, Irina; Ahn, Young Hoon; Nikulin, Sergey; Poloznikov, Andrey; Gazaryan, Irina; Yamamoto, Masayuki; Matsumoto, Mitsuyo; Igarashi, Kazuhiko; Sharma, Sudarshana M; Thomas, Bobby

Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue

靶向 Keap1-Nrf2 通路进行神经治疗的挑战与局限性:Bach1 去抑制疗法的出现

Hushpulian, Dmitry M; Ammal Kaidery, Navneet; Ahuja, Manuj; Poloznikov, Andrey A; Sharma, Sudarshana M; Gazaryan, Irina G; Thomas, Bobby

Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs

从含阿司匹林的前药中鉴定出一种强效的Nrf2置换激活剂

Gaisina, Irina N; Hushpulian, Dmitry M; Gaisin, Arsen M; Kazakov, Eliot H; Ammal Kaidery, Navneet; Ahuja, Manuj; Poloznikov, Andrey A; Gazaryan, Irina G; Thatcher, Gregory R J; Thomas, Bobby

Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease

利用高效合成三萜类化合物靶向Nrf2介导的基因转录,可减轻MPTP诱导的帕金森病小鼠模型中的多巴胺能神经毒性。

Kaidery, Navneet Ammal; Banerjee, Rebecca; Yang, Lichuan; Smirnova, Natalya A; Hushpulian, Dmitry M; Liby, Karen T; Williams, Charlotte R; Yamamoto, Masayuki; Kensler, Thomas W; Ratan, Rajiv R; Sporn, Michael B; Beal, M Flint; Gazaryan, Irina G; Thomas, Bobby