日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface target.

泛癌 N-糖蛋白组学图谱显示,患者来源的异种移植瘤中 FAT2 是一个可操作的表面靶点。

Govindarajan Meinusha, Mejia-Guerrero Salvador, Chafe Shawn C, Khan Shahbaz, Shi Wei, Waas Matthew, Rossotti Martin A, Khoo Amanda, Liu Lydia Y, Ignatchenko Vladimir, Principe Simona, Sepiashvili Lusia, Hussack Greg, Tatari Nazanin, Venugopal Chitra, Miletic Petar, Topley Maxwell, Grewal Shan, McKenna Dillon, Asselstine Lucas C, Sandi Maria-Jose, Pham Nhu-An, Casey Alison, Kim Hyeyeon, Karamboulas Christina, Meens Jalna, Bergqvist Peter, Silva Begonia, Chan Patrick, Cerna-Portillo Liza, Chin Jasmine, Rao-Bhatia Abilasha, Tsao Ming-Sound, Khokha Rama, Su Susie, Xu Wei, Goldstein David, Ailles Laurie, Stambolic Vuk, Liu Fei-Fei, Cummins Emma, Samudio Ismael, Singh Sheila K, Kislinger Thomas

Optimization of synthetic human V(H) affinity and solubility through in vitro affinity maturation and minimal camelization.

通过体外亲和力成熟和最小驼峰化优化合成人V(H)的亲和力和溶解度

Bélanger Kasandra, Wu Cunle, Sulea Traian, van Faassen Henk, Callaghan Deborah, Aubry Annie, Sasseville Marc, Hussack Greg, Tanha Jamshid

Broadly reactive anti-VHH antibodies for characterizing, blocking, or activating nanobody-based CAR-T cells.

用于表征、阻断或激活基于纳米抗体的 CAR-T 细胞的广谱抗 VHH 抗体

McComb Scott, Dupont Bianca, Shepherd Alex, Bennychen Bigitha, Marcil Anne, Tamblyn Laura, Raphael Shalini, Sheff Joey, Hussack Greg, Moraitis Anna N, Wu Cunle, Aubry Annie, Gadoury Christine, Lippens Julie, Pagé Martine, Fortin Annie, Joubert Simon, Lamoureux Linda, Parat Marie, Plante Pierre, Malenfant Félix, Acchione Mauro, Pohankova Petra, Schrag Joe, Acel Andrea, Coutu Mathieu, Smith Emma, El Bakkouri Majida, Hill Jennifer J, Tremblay Tammy-Lynn, Manceur Aziza P, Faulkes Sharlene, Webb John, Zafer Ahmed, Zhu Qin, Nguyen Tina, Pon Robert A, Weeratna Risini D, Arbabi-Ghahroudi Mehdi

Structure of the Fab fragment of a humanized 5E5 antibody to a cancer-specific Tn-MUC1 epitope

人源化5E5抗体Fab片段针对癌症特异性Tn-MUC1表位的结构

Li, Wei; Mandel, Ulla; van Faassen, Henk; Parker, Matthew J; Legg, Max S G; Hussack, Greg; Clausen, Henrik; Evans, Stephen V

A Novel Antigen Design Strategy to Isolate Single-Domain Antibodies that Target Human Nav1.7 and Reduce Pain in Animal Models

一种新型抗原设计策略,用于分离靶向人Nav1.7的单域抗体并减轻动物模型中的疼痛

Martina, Marzia; Banderali, Umberto; Yogi, Alvaro; Arbabi Ghahroudi, Mehdi; Liu, Hong; Sulea, Traian; Durocher, Yves; Hussack, Greg; van Faassen, Henk; Chakravarty, Balu; Liu, Qing Yan; Iqbal, Umar; Ling, Binbing; Lessard, Etienne; Sheff, Joey; Robotham, Anna; Callaghan, Debbie; Moreno, Maria; Comas, Tanya; Ly, Dao; Stanimirovic, Danica

Editorial: Single-domain antibodies-biology, engineering and emerging applications, volume II

社论:单域抗体——生物学、工程学和新兴应用,第二卷

Henry, Kevin A; Hussack, Greg; Gettemans, Jan; Brooks, Cory L

Outer membrane vesicles as a platform for the discovery of antibodies to bacterial pathogens

外膜囊泡作为发现细菌病原体抗体的平台

Lei, Eric K; Azmat, Aruba; Henry, Kevin A; Hussack, Greg

Modulation of toxin production by the flagellar regulon in Clostridium difficile

艰难梭菌鞭毛调节子对毒素产生的调控

Aubry, Annie; Hussack, Greg; Chen, Wangxue; KuoLee, Rhonda; Twine, Susan M; Fulton, Kelly M; Foote, Simon; Carrillo, Catherine D; Tanha, Jamshid; Logan, Susan M

Toxin-specific antibodies for the treatment of Clostridium difficile: current status and future perspectives

毒素特异性抗体在艰难梭菌感染治疗中的应用:现状与展望

Hussack, Greg; Tanha, Jamshid

Intracellular expression of a single domain antibody reduces cytotoxicity of 15-acetyldeoxynivalenol in yeast

单域抗体的细胞内表达可降低15-乙酰脱氧雪腐镰刀菌烯醇对酵母的细胞毒性。

Doyle, Patrick J; Saeed, Hanaa; Hermans, Anne; Gleddie, Steve C; Hussack, Greg; Arbabi-Ghahroudi, Mehdi; Seguin, Charles; Savard, Marc E; Mackenzie, C Roger; Hall, J Christopher