日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DrugBank mining with machine learning reveals novel candidates for BCL-2 inhibition

利用机器学习技术对DrugBank数据库进行挖掘,发现了BCL-2抑制剂的新候选药物

Park, Juwon; Cho, Soyoung; Lee, Hyundo; Choi, Yo Rim; Choi, Dong-Hwa; Jeong, Mi-Young; Lim, Yun-Sook; Hwang, Soon B; Choi, Jiwon

A natural product YSK-A blocks SARS-CoV-2 propagation by targeting multiple host genes

天然产物YSK-A通过靶向多个宿主基因来阻断SARS-CoV-2的传播。

Pham, Thuy X; Huynh, Trang T X; Kim, Bumseok; Lim, Yun-Sook; Hwang, Soon B

Amuvatinib Blocks SARS-CoV-2 Infection at the Entry Step of the Viral Life Cycle.

阿莫替尼在病毒生命周期的进入阶段阻断SARS-CoV-2感染

Huynh Trang T X, Pham Thuy X, Lee Gun-Hee, Lee Jae-Bong, Lee Sung-Geun, Tark Dongseob, Lim Yun-Sook, Hwang Soon B

Hepatitis C Virus Nonstructural 5A Protein Interacts with Telomere Length Regulation Protein: Implications for Telomere Shortening in Patients Infected with HCV

丙型肝炎病毒非结构蛋白5A与端粒长度调节蛋白相互作用:对丙型肝炎病毒感染患者端粒缩短的意义

Lim, Yun-Sook; Nguyen, Men T N; Pham, Thuy X; Huynh, Trang T X; Park, Eun-Mee; Choi, Dong Hwa; Kang, Sang Min; Tark, Dongseob; Hwang, Soon B

Hepatitis C Virus Nonstructural Protein 5A Interacts with Immunomodulatory Kinase IKKε to Negatively Regulate Innate Antiviral Immunity

丙型肝炎病毒非结构蛋白5A与免疫调节激酶IKKε相互作用,从而负向调节先天性抗病毒免疫

Kang, Sang-Min; Park, Ji-Young; Han, Hee-Jeong; Song, Byeong-Min; Tark, Dongseob; Choi, Byeong-Sun; Hwang, Soon B

Asunaprevir, a Potent Hepatitis C Virus Protease Inhibitor, Blocks SARS-CoV-2 Propagation

阿舒那韦是一种强效的丙型肝炎病毒蛋白酶抑制剂,可阻断SARS-CoV-2的传播。

Lim, Yun-Sook; Nguyen, Lap P; Lee, Gun-Hee; Lee, Sung-Geun; Lyoo, Kwang-Soo; Kim, Bumseok; Hwang, Soon B

PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly

PACSIN2 与非结构蛋白 5A 相互作用并调控丙型肝炎病毒的组装

Nguyen, Lap P; Tran, Si C; Suetsugu, Shiro; Lim, Yun-Sook; Hwang, Soon B

Cortactin Interacts with Hepatitis C Virus Core and NS5A Proteins: Implications for Virion Assembly

Cortactin 与丙型肝炎病毒核心蛋白和 NS5A 蛋白相互作用:对病毒颗粒组装的影响

Nguyen, Lap P; Nguyen, Tram T T; Nguyen, Huu C; Pham, Hang T; Han, Kang Min; Choi, Dong Hwa; Park, Eun-Mee; Kang, Sang Min; Tark, Dongseob; Lim, Yun-Sook; Hwang, Soon B

Hepatitis C Virus Downregulates Ubiquitin-Conjugating Enzyme E2S Expression To Prevent Proteasomal Degradation of NS5A, Leading to Host Cells More Sensitive to DNA Damage

丙型肝炎病毒通过下调泛素结合酶E2S的表达来阻止NS5A的蛋白酶体降解,从而导致宿主细胞对DNA损伤更加敏感。

Pham, Hang T; Nguyen, Tram T T; Nguyen, Lap P; Han, Sang-Seop; Lim, Yun-Sook; Hwang, Soon B

Nonstructural Protein 5A Impairs DNA Damage Repair: Implications for Hepatitis C Virus-Mediated Hepatocarcinogenesis

非结构蛋白5A损害DNA损伤修复:对丙型肝炎病毒介导的肝癌发生的影响

Nguyen, Tram T T; Park, Eun-Mee; Lim, Yun-Sook; Hwang, Soon B