日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development and Evaluation of ABI-171, a New Fluoro-Catechin Derivative, for the Treatment of Idiopathic Pulmonary Fibrosis.

开发和评估新型氟儿茶素衍生物 ABI-171 用于治疗特发性肺纤维化

Araldi Gian Luca, Hwang Yu-Wen, Raghu Ganesh

Development of Novel Fluorinated Polyphenols as Selective Inhibitors of DYRK1A/B Kinase for Treatment of Neuroinflammatory Diseases including Parkinson's Disease

开发新型氟化多酚作为DYRK1A/B激酶选择性抑制剂用于治疗包括帕金森病在内的神经炎症性疾病

Araldi, Gian Luca; Hwang, Yu-Wen

Design, synthesis, and biological evaluation of polyphenol derivatives as DYRK1A inhibitors. The discovery of a potentially promising treatment for Multiple Sclerosis

设计、合成和生物学评价多酚衍生物作为DYRK1A抑制剂。发现一种潜在的治疗多发性硬化症的有效方法。

Araldi, Gian Luca; Hwang, Yu-Wen

The role of DYRK1A in neurodegenerative diseases

DYRK1A在神经退行性疾病中的作用

Wegiel, Jerzy; Gong, Cheng-Xin; Hwang, Yu-Wen

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

DYRK1A蛋白过表达在唐氏综合征早期神经纤维缠结变性中的作用

Wegiel, Jerzy; Dowjat, Karol; Kaczmarski, Wojciech; Kuchna, Izabela; Nowicki, Krzysztof; Frackowiak, Janusz; Mazur Kolecka, Bozena; Wegiel, Jarek; Silverman, Wayne P; Reisberg, Barry; Deleon, Mony; Wisniewski, Thomas; Gong, Cheng-Xin; Liu, Fei; Adayev, Tatyana; Chen-Hwang, Mo-Chou; Hwang, Yu-Wen

Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome

Dyrk1A 的过度表达会导致唐氏综合征的神经原纤维变性。

Liu, Fei; Liang, Zhihou; Wegiel, Jerzy; Hwang, Yu-Wen; Iqbal, Khalid; Grundke-Iqbal, Inge; Ramakrishna, Narayan; Gong, Cheng-Xin

Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome

唐氏综合征患者脑内DYRK1A激酶的三体驱动过度表达

Dowjat, Wieslaw K; Adayev, Tatyana; Kuchna, Izabela; Nowicki, Krzysztof; Palminiello, Sonia; Hwang, Yu Wen; Wegiel, Jerzy