日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

One down but many more to go: the state of gene therapy for inherited retinal disease

已解决一个问题,但还有更多问题需要解决:遗传性视网膜疾病的基因疗法现状

Tan, Tien-En; Sun, Christopher Z Y; Poh, Stanley S J; Lim, Joshua; Teo, Jasmin X J; Dey, Sonali; Chua, Zachary W X; Guo, Jing; Wang, Zhenxun; Tay, Hwee Goon; Fenner, Beau J

Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function

光感受器层粘连蛋白驱动人类多能干细胞分化为光感受器祖细胞,从而部分恢复视网膜功能

Hwee Goon Tay, Helder Andre, Vicki Chrysostomou, Swarnaseetha Adusumalli, Jing Guo, Xiaoyuan Ren, Wei Sheng Tan, Jia En Tor, Aida Moreno-Moral, Flavia Plastino, Hammurabi Bartuma, Zuhua Cai, Sai Bo Bo Tun, Veluchamy Amutha Barathi, Gavin Tan Siew Wei, Gianluca Grenci, Li Yen Chong, Arne Holmgren, An

Calcium signaling mediates proliferation of the precursor cells that give rise to the ciliated left-right organizer in the zebrafish embryo

钙信号介导前体细胞的增殖,从而在斑马鱼胚胎中产生纤毛左右组织者

Osama Abdel-Razek, Amanda Marzouk, Madison MacKinnon, Edward T Guy 4th, Sonny A Pohar, Emily Zhushma, Junjie Liu, Isabel Sia, Jason J Gokey, Hwee Goon Tay, Jeffrey D Amack

Corneal Endothelial-like Cells Derived from Induced Pluripotent Stem Cells for Cell Therapy

诱导性多能干细胞来源的角膜内皮样细胞用于细胞治疗

Xiao Yu Ng, Gary S L Peh, Gary Hin-Fai Yam, Hwee Goon Tay, Jodhbir S Mehta

Kupffer's vesicle size threshold for robust left-right patterning of the zebrafish embryo.

库普弗氏囊泡大小阈值对斑马鱼胚胎左右方向的稳定形成至关重要

Gokey Jason J, Ji Yongchang, Tay Hwee Goon, Litts Bridget, Amack Jeffrey D

CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base

CEP162是一种轴丝识别蛋白,可促进纤毛基部纤毛过渡区的组装。

Won-Jing Wang ,Hwee Goon Tay, Rajesh Soni, Geoffrey S Perumal, Mary G Goll, Frank P Macaluso, John M Asara, Jeffrey D Amack, Meng-Fu Bryan Tsou

Lethal giant larvae 2 regulates development of the ciliated organ Kupffer's vesicle

致命巨型幼虫2调控纤毛器官库普弗氏囊泡的发育

Tay, Hwee Goon; Schulze, Sabrina K; Compagnon, Julien; Foley, Fiona C; Heisenberg, Carl-Philipp; Yost, H Joseph; Abdelilah-Seyfried, Salim; Amack, Jeffrey D

A vertebrate-specific Chp-PAK-PIX pathway maintains E-cadherin at adherens junctions during zebrafish epiboly

脊椎动物特有的Chp-PAK-PIX通路在斑马鱼外胚层包被过程中维持粘附连接处的E-钙黏蛋白。

Hwee Goon Tay,Yuen Wai Ng, Ed Manser