日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

LECT2-PHB2 axis: a new mechanistic insight and therapeutic opportunity in alcohol-associated hepatitis

LECT2-PHB2轴：酒精相关性肝炎的新机制见解和治疗契机

期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2025-335259
Li, Hui; Song, Meiyi; Hylemon, Phillip B; Zhou, Huiping
PHB2
肝炎
LECT2
ECT2
发表日期：2025
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Transcriptomics, lipidomics, and single-nucleus RNA sequencing integration: exploring sphingolipids in MASH-HCC progression

转录组学、脂质组学和单核RNA测序整合：探索MASH-HCC进展中的鞘脂

期刊:Cell and Bioscience
影响因子:6.2
doi:10.1186/s13578-025-01362-5
Zeng, Jing; Way, Grayson; Wu, Nan; Jiang, Xixian; Tai, Yun-Ling; Zhao, Derrick; Su, Lianyong; Yan, Qianhua; Wang, Xuan; Gurley, Emily C; Hylemon, Phillip B; Aseem, Sayed Obaidullah; Sanyal, Arun J; Fan, Jiangao; Zhou, Huiping
发表日期：2025
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Intestinal mucosal mitochondrial oxidative phosphorylation worsens with cirrhosis progression and is ameliorated with fecal microbiota transplantation

随着肝硬化的进展，肠黏膜线粒体氧化磷酸化作用恶化，而粪便微生物移植可以改善这一状况。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.186649
Zeng, Jing; Zhao, Derrick; Way, Grayson; Fagan, Andrew; Fuchs, Michael; Puri, Puneet; Davis, Brian C; Wang, Xuan; Gurley, Emily C; Hylemon, Phillip B; Fan, Jian-Gao; Sikaroodi, Masoumeh; Gillevet, Patrick M; Zhou, Huiping; Bajaj, Jasmohan S
信号转导
微生物学
线粒体
肝硬化
磷酸化
发表日期：2025
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Bile acid dysmetabolism in Bangladeshi infants associated with poor linear growth, enteric inflammation, and small intestine bacterial overgrowth

孟加拉国婴儿胆汁酸代谢紊乱与线性生长不良、肠道炎症和小肠细菌过度生长有关

期刊:World Journal of Gastroenterology
影响因子:5.4
doi:10.3748/wjg.v31.i43.111609
Hasan, Farah; Hylemon, Phillip B; Haque, Rashidul; Petri, William A; Faruque, Abu Syed Golam; Kirkpatrick, Beth D; Alam, Madud; Ferdous, Tahsin; Shama, Talat; Moreau, Brett; Ramakrishnan, Girija; Zhou, Huiping; Chesney, Alden; Medrano Garcia, Felix; Smirnova, Ekaterina; Prem, Preethi; Huang, Yingsi; Bojja, Rashmi; Thapaliya, Anubhav; Donowitz, Jeffrey R
炎症
肠炎
炎症/感染
代谢
微生物学
发表日期：2025
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Tailored Levofloxacin Incorporated Extracellular Matrix Nanoparticles for Pulmonary Infections

用于治疗肺部感染的定制左氧氟沙星包封细胞外基质纳米颗粒

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26157453
Patel, Raahi; Moyano, Ignacio; Sakagami, Masahiro; Kang, Jason D; Hylemon, Phillip B; Voynow, Judith A; Heise, Rebecca L
炎症/感染
细胞生物学
发表日期：2025
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Aramchol attenuates fibrosis in mouse models of biliary fibrosis and blocks the TGFβ-induced fibroinflammatory mediators in cholangiocytes.

Aramchol 可减轻胆道纤维化小鼠模型中的纤维化，并阻断胆管细胞中 TGFβ 诱导的纤维炎症介质

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000748
Aseem Sayed Obaidullah, Wang Jing, Kalaiger Maleeha F, Way Grayson, Zhao Derrick, Tai Yunling, Gurley Emily, Zeng Jing, Wang Xuan, Cowart Lauren Ashley, Huebert Robert C, Hylemon Phillip B, Jalan-Sakrikar Nidhi, Sanyal Arun J, Zhou Huiping
细胞生物学
Mouse
炎症
发表日期：2025
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Gut Microbiome and Bile Acid Interactions: Mechanistic Implications for Cholangiocarcinoma Development, Immune Resistance, and Therapy

肠道微生物群与胆汁酸相互作用：对胆管癌发生发展、免疫抵抗和治疗的机制意义

期刊:American Journal of Pathology
影响因子:3.6
doi:10.1016/j.ajpath.2024.11.004
Wu, Nan; Bayatpour, Sareh; Hylemon, Phillip B; Aseem, Sayed O; Brindley, Paul J; Zhou, Huiping
肿瘤
肿瘤免疫
微生物学
胆管癌
免疫/内分泌
发表日期：2025
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Bile acid dysmetabolism in Bangladeshi infants is associated with poor linear growth, enteric inflammation, and small intestine bacterial overgrowth.

孟加拉国婴儿的胆汁酸代谢紊乱与线性生长不良、肠道炎症和小肠细菌过度生长有关

期刊:
影响因子:
doi:10.1101/2025.02.04.25321650
Hasan Farah, Hylemon Phillip B, Haque Rashidul, Petri William A Jr, Faruque Abu S G, Kirkpatrick Beth D, Alam Masud, Ferdous Tahsin, Shama Talat, Moreau Brett, Ramakrishnan Girija, Zhou Huiping, Chesney Alden, Garcia Felix Medrano, Smirnova Ekaterina, Prem Preethi, Huang Yingsi, Bojja Rashmi, Thapaliya Anubhav, Donowitz Jeffrey R
代谢
肠炎
炎症
发表日期：2025
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The RIVET RCT: Rifamycin SV MMX improves muscle mass, physical function, and ammonia in cirrhosis and minimal encephalopathy

RIVET RCT：利福霉素SV MMX可改善肝硬化和轻微肝性脑病患者的肌肉量、身体机能和血氨水平。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000384
Bajaj, Jasmohan S; Fagan, Andrew; Gavis, Edith A; Mousel, Travis; Gallagher, Mary L; Puri, Puneet; Fuchs, Michael; Davis, Brian C; Hylemon, Phillip B; Zhou, Huiping; Ahluwalia, Vishwadeep; Cadrain, Robert; Sikaroodi, Masoumeh; Gillevet, Patrick M
肝硬化
神经科学
多发性骨髓瘤
发表日期：2024
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Sphingosine kinase 2 (SphK2) depletion alters redox metabolism and enhances inflammation in a diet-induced MASH mouse model

鞘氨醇激酶 2 (SphK2) 的缺失会改变氧化还原代谢，并加剧饮食诱导的 MASH 小鼠模型中的炎症反应。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000570
Jackson, Kaitlyn G; Zhao, Derrick; Su, Lianyong; Lipp, Marissa K; Toler, Cameron; Idowu, Michael; Yan, Qianhua; Wang, Xuan; Gurley, Emily; Wu, Nan; Puri, Puneet; Chen, Qun; Lesnefsky, Edward J; Dupree, Jeffrey L; Hylemon, Phillip B; Zhou, Huiping
炎症/感染
信号转导
炎症
代谢
发表日期：2024
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