FAK inhibition in ovarian cancer releases omega-3 fatty acids to program CXCL13-producing anti-tumor resident peritoneal macrophages.
卵巢癌中 FAK 抑制可释放 omega-3 脂肪酸，从而激活产生 CXCL13 的抗肿瘤驻留腹膜巨噬细胞。
期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2026.117009
Chen Xiao Lei, Tharp Kevin M, Ojalill Marjaana, Ozmadenci Duygu, Boyer Antonia, Haanen Terrance J 3rd, Lawson Christine, Lee Hyojae J, Xia Marvin, Tahon Elise, Zhang Yichi, Minor Cray, Khan Safir Ullah, Anderson Colin C, Nemkov Travis, Rose Michael, Estrada Monica V, Molinolo Alfredo A, Warren Elias, Penalosa Patrick, Eskander Ramez N, McHale Michael T, Wang Shizhen E, Connolly Denise C, Fisch Kathleen M, Stupack Dwayne G, Schlaepfer David D
卵巢癌
细胞生物学
巨噬细胞
FAK
XCL1
CXCL1
CXCL13
CXCL1
巨噬细胞
