日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A protein dynamics-based deep learning model enhances predictions of fitness and epistasis

基于蛋白质动力学的深度学习模型增强了对适应度和上位性的预测

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2502444122
Huynh, Ngoc; Kazan, I Can; Lu, Jin; Kolbaba-Kartchner, Bethany; Mills, Jeremy H; Ozkan, S Banu
发表日期：2025
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Dynamic Allostery: Evolution's Double-Edged Sword in Protein Function and Disease

动态变构：蛋白质功能和疾病中的进化双刃剑

期刊:Journal of Molecular Biology
影响因子:4.5
doi:10.1016/j.jmb.2025.169175
Campitelli, Paul; Kazan, I Can; Hamilton, Sean; Ozkan, S Banu
发表日期：2025
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Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately

人类 TRPM8 通道的冷和薄荷醇感应功能是独立进化的

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.adm9228
Dustin D Luu, Nikhil Ramesh, I Can Kazan, Karan H Shah, Gourab Lahiri, Miyeko D Mana, S Banu Ozkan, Wade D Van Horn
信号转导
Human
发表日期：2024
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Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics

通过整合候选适应性多态性与蛋白质动力学，揭示SARS-CoV-2刺突蛋白分子适应的一些机制基础

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.92063
Ose, Nicholas James; Campitelli, Paul; Modi, Tushar; Kazan, I Can; Kumar, Sudhir; Ozkan, Sefika Banu
SARS-CoV-2
发表日期：2024
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Engineering gain-of-function mutants of a WW domain by dynamics and structural analysis

通过动力学和结构分析构建WW结构域的功能获得型突变体

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4759
Lu, Jin; Rahman, Mohammad Imtiazur; Kazan, I Can; Halloran, Nicholas R; Bobkov, Andrey A; Ozkan, S Banu; Ghirlanda, Giovanna
发表日期：2023
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Allosteric regulatory control in dihydrofolate reductase is revealed by dynamic asymmetry

二氢叶酸还原酶的变构调节控制通过动态不对称性揭示

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4700
Kazan, I Can; Mills, Jeremy H; Ozkan, S Banu
发表日期：2023
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Investigating the allosteric response of the PICK1 PDZ domain to different ligands with all-atom simulations

利用全原子模拟研究PICK1 PDZ结构域对不同配体的变构响应

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4474
Stevens, Amy O; Kazan, I Can; Ozkan, Banu; He, Yi
PICK1
发表日期：2022
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Dynamic coupling of residues within proteins as a mechanistic foundation of many enigmatic pathogenic missense variants

蛋白质内部残基的动态耦合是许多神秘致病性错义变异的机制基础

期刊:PLoS Computational Biology
影响因子:3.6
doi:10.1371/journal.pcbi.1010006
Ose, Nicholas J; Butler, Brandon M; Kumar, Avishek; Kazan, I Can; Sanderford, Maxwell; Kumar, Sudhir; Ozkan, S Banu
发表日期：2022
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Randomized controlled study of a diagnosis and treatment plan for moderate coronavirus disease 2019 that integrates Traditional Chinese and Western Medicine

一项针对中西医结合的冠状病毒病中度症状诊断和治疗方案的随机对照研究

期刊:
影响因子:
doi:10.19852/j.cnki.jtcm.20210220.001
Wenguang, Xia; Chanjuan, Zheng; Jixian, Zhang; Min, Huang; Qinglin, L I; Can, Duan; Zhengliang, L I; Cunyu, Fan; Yilong, Zou; Bo, X U; Fengwen, Yang; Qingquan, Liu
微生物学
发表日期：2022
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The Role of Rigid Residues in Modulating TEM-1 β-Lactamase Function and Thermostability

刚性残基在调节TEM-1 β-内酰胺酶功能和热稳定性中的作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms22062895
Kolbaba-Kartchner, Bethany; Kazan, I Can; Mills, Jeremy H; Ozkan, S Banu
发表日期：2021
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