Iacobucci Gary相关文献与解析，生知库 | 链接生命科学的每一步

Opposing roles for GSK3Î² and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington's disease.

亨廷顿病中神经元功能障碍和细胞死亡期间，GSK3β 和 ERK1 依赖的亨廷顿蛋白磷酸化起着相反的作用

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-07524-0

Krzystek Thomas J, Rathnayake Rasika, Zeng Jia, Huang Jing, Iacobucci Gary, Yu Michael C, Gunawardena Shermali

Calcium- and calmodulin-dependent inhibition of NMDA receptor currents

钙离子和钙调蛋白依赖性NMDA受体电流抑制

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2023.12.018

Iacobucci, Gary J; Popescu, Gabriela K

信号转导

发表日期：2024

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Estimating the Ca(2+) Block of NMDA Receptors with Single-Channel Electrophysiology

利用单通道电生理学方法估算NMDA受体的Ca(2+)阻滞

期刊:Methods in Molecular Biology

影响因子:

doi:10.1007/978-1-0716-3830-9_9

Iacobucci, Gary J; Popescu, Gabriela K

信号转导

发表日期：2024

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Allosteric Site Mediates Inhibition of Tonic NMDA Receptor Activity by Low Dose Ketamine

低剂量氯胺酮通过变构位点介导对NMDA受体强直活性的抑制

期刊:

影响因子:

doi:10.21203/rs.3.rs-3304783/v1

Popescu, Gabriela; Abbott, Jamie; Wen, Han; Liu, Beiying; Gupta, Sheila; Iacobucci, Gary; Zheng, Wenjun

Complex functional phenotypes of NMDA receptor disease variants

NMDA受体疾病变异体的复杂功能表型

期刊:Molecular Psychiatry

影响因子:10.1

doi:10.1038/s41380-022-01774-6

Iacobucci, Gary J; Liu, Beiying; Wen, Han; Sincox, Brittany; Zheng, Wenjun; Popescu, Gabriela K

信号转导

发表日期：2022

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Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors

亚基间的相互作用能够稳定开放状态，从而介导NMDA受体的门控机制。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2007511118

Iacobucci, Gary J; Wen, Han; Helou, Matthew; Liu, Beiying; Zheng, Wenjun; Popescu, Gabriela K

信号转导

发表日期：2021

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Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease.

过量的 Rab4 可以挽救亨廷顿病中由 HTT-Rab4 轴突运输缺陷引起的突触和行为功能障碍

期刊:Acta Neuropathologica Communications

影响因子:5.7

doi:10.1186/s40478-020-00964-z

White Joseph A 2nd, Krzystek Thomas J, Hoffmar-Glennon Hayley, Thant Claire, Zimmerman Katherine, Iacobucci Gary, Vail Julia, Thurston Layne, Rahman Saad, Gunawardena Shermali

Ethanol stimulates the in vivo axonal movement of neuropeptide dense-core vesicles in Drosophila motor neurons

乙醇刺激果蝇运动神经元中神经肽致密核心囊泡的体内轴突运动

期刊:Journal of Neurochemistry

影响因子:4

doi:10.1111/jnc.14230

Iacobucci, Gary J; Gunawardena, Shermali

Drosophila

发表日期：2018

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Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling

利用粗粒化建模探究NMDA受体激活的结构动力学

期刊:Biophysical Journal

影响因子:3.1

doi:10.1016/j.bpj.2017.04.043

Zheng, Wenjun; Wen, Han; Iacobucci, Gary J; Popescu, Gabriela K

信号转导

发表日期：2017

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Allosteric inhibition of NMDA receptors by low dose ketamine.

低剂量氯胺酮对NMDA受体的变构抑制作用

Opposing roles for GSK3Î² and ERK1-dependent phosphorylation of huntingtin during neuronal dysfunction and cell death in Huntington's disease.

亨廷顿病中神经元功能障碍和细胞死亡期间，GSK3β 和 ERK1 依赖的亨廷顿蛋白磷酸化起着相反的作用

Calcium- and calmodulin-dependent inhibition of NMDA receptor currents

钙离子和钙调蛋白依赖性NMDA受体电流抑制

Estimating the Ca(2+) Block of NMDA Receptors with Single-Channel Electrophysiology

利用单通道电生理学方法估算NMDA受体的Ca(2+)阻滞

Allosteric Site Mediates Inhibition of Tonic NMDA Receptor Activity by Low Dose Ketamine

低剂量氯胺酮通过变构位点介导对NMDA受体强直活性的抑制

Complex functional phenotypes of NMDA receptor disease variants

NMDA受体疾病变异体的复杂功能表型

Cross-subunit interactions that stabilize open states mediate gating in NMDA receptors

亚基间的相互作用能够稳定开放状态，从而介导NMDA受体的门控机制。

Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease.

过量的 Rab4 可以挽救亨廷顿病中由 HTT-Rab4 轴突运输缺陷引起的突触和行为功能障碍

Ethanol stimulates the in vivo axonal movement of neuropeptide dense-core vesicles in Drosophila motor neurons

乙醇刺激果蝇运动神经元中神经肽致密核心囊泡的体内轴突运动

Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling

利用粗粒化建模探究NMDA受体激活的结构动力学