日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrating Surface Plasmon Resonance and Docking Analysis for Mechanistic Insights of Tryptase Inhibitors

整合表面等离子体共振和分子对接分析以深入了解类胰蛋白酶抑制剂的作用机制

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30061338
Porta, Alessia; Manelfi, Candida; Talarico, Carmine; Beccari, Andrea Rosario; Brindisi, Margherita; Summa, Vincenzo; Iaconis, Daniela; Gobbi, Marco; Beeg, Marten
发表日期：2025
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Dual-Site Inhibition of SARS-CoV-2 RNA-Dependent RNA Polymerase by Small Molecules Able to Block Viral Replication Identified through a Computer-Aided Drug Discovery Approach

通过计算机辅助药物发现方法鉴定出能够阻断SARS-CoV-2 RNA依赖性RNA聚合酶双位点抑制的小分子

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.5c00517
Malune, Paolo; Iaconis, Daniela; Manelfi, Candida; Giunta, Stefano; Emmolo, Roberta; Lunghini, Filippo; Paulis, Annalaura; Talarico, Carmine; Corona, Angela; Beccari, Andrea Rosario; Tramontano, Enzo; Esposito, Francesca
SARS-CoV-2
发表日期：2025
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Thiol-Reactive or Redox-Active: Revising a Repurposing Screen Led to a New Invalidation Pipeline and Identified a True Noncovalent Inhibitor Against Papain-like Protease from SARS-CoV-2.

硫醇反应性或氧化还原活性：修改重新定位筛选导致新的无效化流程，并鉴定出针对 SARS-CoV-2 木瓜蛋白酶样蛋白酶的真正非共价抑制剂

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.4c00325
Kuzikov Maria, Morasso Stefano, Reinshagen Jeanette, Wolf Markus, Monaco Vittoria, Cozzolino Flora, Golič Grdadolnik Simona, Šket Primož, Plavec Janez, Iaconis Daniela, Summa Vincenzo, Corona Angela, Paulis Annalaura, Esposito Francesca, Tramontano Enzo, Monti Maria, Beccari Andrea R, Manelfi Candida, Windshügel Björn, Gribbon Philip, Storici Paola, Zaliani Andrea
炎症/感染
新冠
发表日期：2025
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SARS-CoV-2 Entry Can Be Mimicked in C. elegans Expressing Human ACE2: A New Tool for Pharmacological Studies

SARS-CoV-2病毒入侵可在表达人ACE2的秀丽隐杆线虫中模拟：一种新的药理学研究工具

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v17101387
Romeo, Margherita; Baroni, Sara; Barzago, Maria Monica; Gambini, Samuela; De Luigi, Ada; Iaconis, Daniela; Beccari, Andrea Rosario; Fratelli, Maddalena; Diomede, Luisa
SARS-CoV-2
C. elegans
微生物学
Human
ACE2
发表日期：2025
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Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants

雷洛昔芬作为抗SARS-CoV-2及其变种病毒的潜在药物的特性分析

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-022-04961-z
Iaconis, Daniela; Bordi, Licia; Matusali, Giulia; Talarico, Carmine; Manelfi, Candida; Cesta, Maria Candida; Zippoli, Mara; Caccuri, Francesca; Bugatti, Antonella; Zani, Alberto; Filippini, Federica; Scorzolini, Laura; Gobbi, Marco; Beeg, Marten; Piotti, Arianna; Montopoli, Monica; Cocetta, Veronica; Bressan, Silvia; Bucci, Enrico M; Caruso, Arnaldo; Nicastri, Emanuele; Allegretti, Marcello; Beccari, Andrea R
微生物学
SARS-CoV-2
发表日期：2022
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L-Methionine Protects against Oxidative Stress and Mitochondrial Dysfunction in an In Vitro Model of Parkinson's Disease

L-蛋氨酸在帕金森病体外模型中具有抵抗氧化应激和线粒体功能障碍的作用

期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox10091467
Catanesi, Mariano; Brandolini, Laura; d'Angelo, Michele; Benedetti, Elisabetta; Tupone, Maria Grazia; Alfonsetti, Margherita; Cabri, Enrico; Iaconis, Daniela; Fratelli, Maddalena; Cimini, Annamaria; Castelli, Vanessa; Allegretti, Marcello
毒理研究
氧化应激
帕金森
神经科学
线粒体
发表日期：2021
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S-Carboxymethyl Cysteine Protects against Oxidative Stress and Mitochondrial Impairment in a Parkinson's Disease In Vitro Model

S-羧甲基半胱氨酸在帕金森病体外模型中具有抵抗氧化应激和线粒体损伤的作用

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines9101467
Catanesi, Mariano; Brandolini, Laura; d'Angelo, Michele; Tupone, Maria Grazia; Benedetti, Elisabetta; Alfonsetti, Margherita; Quintiliani, Massimiliano; Fratelli, Maddalena; Iaconis, Daniela; Cimini, Annamaria; Castelli, Vanessa; Allegretti, Marcello
毒理研究
氧化应激
帕金森
神经科学
线粒体
发表日期：2021
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Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease

COX7B基因突变会导致小眼畸形伴线性皮肤病变，这是一种非典型的线粒体疾病。

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2012.09.016
Indrieri, Alessia; van Rahden, Vanessa Alexandra; Tiranti, Valeria; Morleo, Manuela; Iaconis, Daniela; Tammaro, Roberta; D'Amato, Ilaria; Conte, Ivan; Maystadt, Isabelle; Demuth, Stephanie; Zvulunov, Alex; Kutsche, Kerstin; Zeviani, Massimo; Franco, Brunella
线粒体
发表日期：2012
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Mutations of the mitochondrial holocytochrome c-type synthase in X-linked dominant microphthalmia with linear skin defects syndrome

X连锁显性小眼畸形伴线性皮肤缺陷综合征中线粒体全细胞色素c型合成酶的突变

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1086/508474
Wimplinger, Isabella; Morleo, Manuela; Rosenberger, Georg; Iaconis, Daniela; Orth, Ulrike; Meinecke, Peter; Lerer, Israela; Ballabio, Andrea; Gal, Andreas; Franco, Brunella; Kutsche, Kerstin
细胞生物学
线粒体
发表日期：2006
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