Genotype-Tailored ERK/MAPK Pathway and HDAC Inhibition Rewires the Apoptotic Rheostat to Trigger Colorectal Cancer Cell Death
基因型定制的 ERK/MAPK 通路和 HDAC 抑制重新连接凋亡变阻器,引发结直肠癌细胞死亡
期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-22-0101
Laura J Jenkins, Ian Y Luk, W Douglas Fairlie, Erinna F Lee, Michelle Palmieri, Kael L Schoffer, Tao Tan, Irvin Ng, Natalia Vukelic, Sharon Tran, Janson W T Tse, Rebecca Nightingale, Zakia Alam, Fiona Chionh, George Iatropoulos, Matthias Ernst, Shoukat Afshar-Sterle, Jayesh Desai, Peter Gibbs, Olive
信号转导
细胞生物学
肿瘤
肠癌
肿瘤细胞
WB
Apoptosis
MAPK/ERK