Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers
PAK4 抑制剂 KPT9274 在 KRASG12C 突变型胰腺癌和肺癌临床前模型中增强了 KRASG12C 抑制剂的抗癌功效
期刊:Molecular Cancer Therapeutics
影响因子:5.3
doi:10.1158/1535-7163.MCT-23-0251
Husain Yar Khan, Misako Nagasaka, Amro Aboukameel, Osama Alkhalili, Md Hafiz Uddin, Sahar F Bannoura, Yousef Mzannar, Ibrahim Azar, Eliza W Beal, Miguel E Tobon, Steve H Kim, Rafic Beydoun, Erkan Baloglu, William Senapedis, Bassel F El-Rayes, Philip A Philip, Ramzi M Mohammad, Anthony F Shields, Moh
代谢
肿瘤
肺癌
胰腺癌
FCM
IF
IHC-P
WB
Human
G3P
