日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pitfalls and Rewards of Setting Up a Liquid Biopsy Approach for the Detection of Driver Mutations in Circulating Tumor DNAs: Our Institutional Experience

利用液体活检方法检测循环肿瘤DNA中的驱动基因突变:我们的机构经验及其挑战

Chen, Michelle; Jian, Damon; Sidorov, Maxim; Woo, Rinette W L; Kim, Angela; Stone, David E; Nazarian, Ari; Nosrati, Mehdi; Ice, Ryan J; de Semir, David; Dar, Altaf A; Luštrik, Roman; Kokošar, Janez; Ausec, Luka; Rowbotham, Michael C; Tranah, Gregory J; Kashani-Sabet, Mohammed; Soroceanu, Liliana; McAllister, Sean D; Desprez, Pierre-Yves

Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies

在黑色素瘤患者来源的异种移植模型中,药物反应是保守的,这有助于发现新的药物联合疗法。

Ice, Ryan J; Chen, Michelle; Sidorov, Max; Le Ho, Tam; Woo, Rinette W L; Rodriguez-Brotons, Aida; Luu, Tri; Jian, Damon; Kim, Kevin B; Leong, Stanley P; Kim, HanKyul; Kim, Angela; Stone, Des; Nazarian, Ari; Oh, Alyssia; Tranah, Gregory J; Nosrati, Mehdi; de Semir, David; Dar, Altaf A; Chang, Stephen; Desprez, Pierre-Yves; Kashani-Sabet, Mohammed; Soroceanu, Liliana; McAllister, Sean D

Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer.

Eribulin 与 Aurora A 抑制剂 MLN8237 联合使用可预防乳腺癌转移性定植并诱导细胞毒性自噬

Kozyreva Varvara K, Kiseleva Anna A, Ice Ryan J, Jones Brandon C, Loskutov Yuriy V, Matalkah Fatimah, Smolkin Matthew B, Marinak Kristina, Livengood Ryan H, Salkeni Mohamad A, Wen Sijin, Hazard Hannah W, Layne Ginger P, Walsh Callee M, Cantrell Pamela S, Kilby Greg W, Mahavadi Sricharan, Shah Neal, Pugacheva Elena N

Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins

促转移蛋白NEDD9通过Caveolin-1依赖的整合素运输调控单个细胞的迁移

Kozyulina, Polina Y; Loskutov, Yuriy V; Kozyreva, Varvara K; Rajulapati, Anuradha; Ice, Ryan J; Jones, Brandon C; Pugacheva, Elena N

NEDD9 depletion leads to MMP14 inactivation by TIMP2 and prevents invasion and metastasis.

NEDD9 的缺失导致 TIMP2 使 MMP14 失活,从而阻止侵袭和转移

McLaughlin Sarah L, Ice Ryan J, Rajulapati Anuradha, Kozyulina Polina Y, Livengood Ryan H, Kozyreva Varvara K, Loskutov Yuriy V, Culp Mark V, Weed Scott A, Ivanov Alexey V, Pugacheva Elena N