日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Differential transcriptomic and metabolomic landscape between human hearts donated after cardiac vs brain death

心脏死亡后捐献的人类心脏与脑死亡后捐献的人类心脏之间转录组和代谢组的差异图谱

期刊:Journal of Heart and Lung Transplantation
影响因子:6
doi:10.1016/j.healun.2026.03.014
Sicim, Hüseyin; Abou El Ela, Ashraf; Lu, Shuyang; Karunasumetta, Chananya; Danesh, Sina; Knop, Gustavo; Azzam, Fuad Al; Gao, Wenbin; Wang, Ying; Zhu, Wuqiang; Pagani, Francis D; Lei, Ienglam; Tang, Paul C
代谢
神经科学
发表日期：2026
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Mineralocorticoid receptor phase separation modulates cardiac preservation.

盐皮质激素受体相分离调节心脏保护

期刊:Nature Cardiovascular Research
影响因子:10.8
doi:10.1038/s44161-025-00653-x
Lei Ienglam, Sicim Hüseyin, Gao Wenbin, Huang Wei, Noly Pierre Emmanuel, Pergande Melissa R, Wilson Mallory C, Lee Aurora, Liu Liu, Abou El Ela Ashraf, Jiang Mulan, Saddoughi Sahar A, Pober Jordan S, Platt Jeffrey L, Cascalho Marilia, Pagani Francis D, Chen Y Eugene, Pitt Bertram, Wang Zhong, Mortensen Richard M, Ge Ying, Tang Paul C
心血管
发表日期：2025
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Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest

盐皮质激素受体拮抗剂可减少心脏手术后房性心律失常，并减弱心脏停搏引起的房性应激反应

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.125.043661
Danesh, Sina; Khan, Fazal; Chopko, Trevor; Lee, Aurora; Huo, Ran; Lu, Shuyang; Tam, Vincy; Gao, Wenbin; Todd, Austin; Maleszewski, Joseph J; Pagani, Francis D; Schaff, Hartzell; Chen, Y Eugene; Friedman, Paul A; Oral, Hakan; Metra, Marco; Pitt, Bertram; Lei, Ienglam; Tang, Paul C
信号转导
免疫/内分泌
发表日期：2025
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Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest

盐皮质激素受体拮抗剂可减少心脏手术后房性心律失常，并减弱心脏停搏引起的房性应激反应

期刊:
影响因子:
doi:10.1101/2025.02.24.639999
Danesh, Sina; Khan, Fazal; Chopko, Trevor; Lee, Aurora; Huo, Ran; Lu, Shuyang; Tam, Vincy; Safi, Pedro Fincatto; Gao, Wenbin; Todd, Austin; Pagani, Francis D; Maleszewski, Joseph J; Schaff, Hartzell; Friedman, Paul A; Oral, Hakan; Metra, Marco; Pitt, Bertram; Lei, Ienglam; Tang, Paul C
免疫/内分泌
信号转导
发表日期：2025
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Extracellular Matrix Alterations in Chronic Ischemic Cardiomyopathy Revealed by Quantitative Proteomics

定量蛋白质组学揭示慢性缺血性心肌病中细胞外基质的改变

期刊:
影响因子:
doi:10.1101/2025.05.23.655833
Buck, Kevin M; Rogers, Holden T; Gregorich, Zachery R; Mann, Morgan W; Aballo, Timothy J; Gao, Zhan; Chapman, Emily A; Perciaccante, Andrew J; Price, Scott J; Lei, Ienglam; Tang, Paul C; Ge, Ying
心血管
心肌病
细胞生物学
发表日期：2025
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Extracellular matrix alterations in chronic ischemic cardiomyopathy revealed by quantitative proteomics

定量蛋白质组学揭示慢性缺血性心肌病中细胞外基质的改变

期刊:JCI Insight
影响因子:
doi:10.1172/jci.insight.196933
Buck, Kevin M; Rogers, Holden T; Gregorich, Zachery R; Mann, Morgan W; Aballo, Timothy J; Gao, Zhan; Chapman, Emily A; Perciaccante, Andrew J; Price, Scott J; Lei, Ienglam; Tang, Paul C; Ge, Ying
心血管
心肌病
细胞生物学
发表日期：2025
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14-3-3 binding motif phosphorylation disrupts Hdac4-organized condensates to stimulate cardiac reprogramming

14-3-3 结合基序磷酸化破坏 Hdac4 组织的凝聚物，刺激心脏重编程

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2024.114054
Liu Liu, Ienglam Lei, Shuo Tian, Wenbin Gao, Yijing Guo, Zhaokai Li, Ziad Sabry, Paul Tang, Y Eugene Chen, Zhong Wang
表观遗传
发表日期：2024
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Metabolic reprogramming by immune-responsive gene 1 up-regulation improves donor heart preservation and function

通过免疫反应基因 1 上调进行代谢重编程可改善供体心脏的保存和功能

期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.ade3782
Ienglam Lei, Wei Huang, Pierre Emmanuel Noly, Suyash Naik, Miriyam Ghali, Liu Liu, Francis D Pagani, Ashraf Abou El Ela, Jordan S Pober, Bertram Pitt, Jeffrey L Platt, Marilia Cascalho, Zhong Wang, Y Eugene Chen, Richard M Mortensen, Paul C Tang
代谢
免疫
发表日期：2023
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Mitral regurgitation severity at left ventricular assist device implantation is associated with distinct myocardial transcriptomic signatures

左心室辅助装置植入时二尖瓣反流的严重程度与特定的心肌转录组特征相关

期刊:Journal of Thoracic and Cardiovascular Surgery
影响因子:4.4
doi:10.1016/j.jtcvs.2021.08.061
Duggal, Neal M; Lei, Ienglam; Wu, Xiaoting; Aaronson, Keith D; Pagani, Francis D; Lam, Hugo Y-K; Tang, Paul C
发表日期：2023
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Defining the Sarcomeric Proteoform Landscape in Ischemic Cardiomyopathy by Top-Down Proteomics

利用自上而下的蛋白质组学方法定义缺血性心肌病中的肌节蛋白质组图谱

期刊:Journal of Proteome Research
影响因子:3.6
doi:10.1021/acs.jproteome.2c00729
Chapman, Emily A; Aballo, Timothy J; Melby, Jake A; Zhou, Tianhua; Price, Scott J; Rossler, Kalina J; Lei, Ienglam; Tang, Paul C; Ge, Ying
心血管
心肌病
发表日期：2023
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