日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mucosal adenovirus vaccine boosting elicits IgA and durably prevents XBB.1.16 infection in nonhuman primates

黏膜腺病毒疫苗加强免疫可诱导产生 IgA,并持久预防非人灵长类动物的 XBB.1.16 感染。

Matthew Gagne ,Barbara J Flynn ,Shayne F Andrew ,Josue Marquez ,Dillon R Flebbe ,Anna Mychalowych ,Evan Lamb ,Meredith E Davis-Gardner ,Matthew R Burnett ,Leonid A Serebryannyy ,Bob C Lin ,Zohar E Ziff ,Erin Maule ,Robin Carroll ,Mursal Naisan ,Yogita Jethmalani ,Laurent Pessaint ,John-Paul M Todd ,Nicole A Doria-Rose ,James Brett Case ,Igor P Dmitriev ,Elena A Kashentseva ,Baoling Ying ,Alan Dodson ,Katelyn Kouneski ,Sijy O'Dell ,Bushra Wali ,Madison Ellis ,Sucheta Godbole ,Farida Laboune ,Amy R Henry ,I-Ting Teng ,Danyi Wang ,Lingshu Wang ,Qiong Zhou ,Serge Zouantchangadou ,Alex Van Ry ,Mark G Lewis ,Hanne Andersen ,Peter D Kwong ,David T Curiel ,Mario Roederer ,Martha C Nason ,Kathryn E Foulds ,Mehul S Suthar ,Michael S Diamond ,Daniel C Douek ,Robert A Seder

Adenoviral vectors infect B lymphocytes in vivo

腺病毒载体在体内感染B淋巴细胞

Paul J Rice-Boucher ,Samir Andrade Mendonça ,Aluet Borrego Alvarez ,Alexandria J Sturtz ,Reka Lorincz ,Igor P Dmitriev ,Elena A Kashentseva ,Zhi Hong Lu ,Rosa Romano ,Mark Selby ,Kunal Pingale ,David T Curiel

Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation

基于标签/捕获器生物共轭设计新型模块化腺病毒 mRNA 递送平台

Kexin Geng, Paul J Rice-Boucher, Elena A Kashentseva, Igor P Dmitriev, Zhi Hong Lu, S Peter Goedegebuure, William E Gillanders, David T Curiel

Efficient Genome Editing Achieved via Plug-and-Play Adenovirus Piggyback Transport of Cas9/gRNA Complex on Viral Capsid Surface

通过即插即用型腺病毒搭载运输病毒衣壳表面的 Cas9/gRNA 复合物实现高效的基因组编辑

Zhi Hong Lu, Jie Li, Igor P Dmitriev, Elena A Kashentseva, David T Curiel

Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody

利用骆驼单域抗体进行先进的基因工程实现腺病毒的体内靶向

Myungeun Lee, Zhi Hong Lu, Charles B Shoemaker, Jacqueline M Tremblay, Bradley St Croix, Steven Seaman, Rebeca Gonzalez-Pastor, Elena A Kashentseva, Igor P Dmitriev, David T Curiel

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

鼻内疫苗可持久保护小鼠免受SARS-CoV-2变种病毒感染。

Ahmed O Hassan ,Swathi Shrihari ,Matthew J Gorman ,Baoling Ying ,Dansu Yuan ,Saravanan Raju ,Rita E Chen ,Igor P Dmitriev ,Elena Kashentseva ,Lucas J Adams ,Colin Mann ,Meredith E Davis-Gardner ,Mehul S Suthar ,Pei-Yong Shi ,Erica Ollmann Saphire ,Daved H Fremont ,David T Curiel ,Galit Alter ,Michael S Diamond

Evaluation of tumor immunity after administration of conditionally replicative adenoviral vector in canine osteosarcoma patients

评估犬骨肉瘤患者接受条件复制型腺病毒载体治疗后的肿瘤免疫情况

Payal Agarwal ,Elizabeth A Gammon ,Maninder Sandey ,Stephanie S Lindley ,Jey W Koehler ,Brad M Matz ,Annette N Smith ,Elena A Kashentseva ,Igor P Dmitriev ,David T Curiel ,Bruce F Smith

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

单剂量鼻内接种ChAd疫苗可保护上下呼吸道免受SARS-CoV-2病毒感染。

Ahmed O Hassan ,Natasha M Kafai ,Igor P Dmitriev ,Julie M Fox ,Brittany K Smith ,Ian B Harvey ,Rita E Chen ,Emma S Winkler ,Alex W Wessel ,James Brett Case ,Elena Kashentseva ,Broc T McCune ,Adam L Bailey ,Haiyan Zhao ,Laura A VanBlargan ,Ya-Nan Dai ,Meisheng Ma ,Lucas J Adams ,Swathi Shrihari ,Jonathan E Danis ,Lisa E Gralinski ,Yixuan J Hou ,Alexandra Schäfer ,Arthur S Kim ,Shamus P Keeler ,Daniela Weiskopf ,Ralph S Baric ,Michael J Holtzman ,Daved H Fremont ,David T Curiel ,Michael S Diamond

Targeting Tumor Neoangiogenesis via Targeted Adenoviral Vector to Achieve Effective Cancer Gene Therapy for Disseminated Neoplastic Disease

通过靶向腺病毒载体靶向肿瘤新血管生成实现播散性肿瘤疾病的有效癌症基因治疗

Myungeun Lee, Zhi Hong Lu, Jie Li, Elena A Kashentseva, Igor P Dmitriev, Samir A Mendonca, David T Curiel

A New Gorilla Adenoviral Vector with Natural Lung Tropism Avoids Liver Toxicity and Is Amenable to Capsid Engineering and Vector Retargeting

具有天然肺向性的新型大猩猩腺病毒载体可避免肝毒性,且易于进行衣壳工程和载体重定向

Zhi Hong Lu, Igor P Dmitriev, Douglas E Brough, Elena A Kashentseva, Jie Li, David T Curiel