Ikenouchi相关文献与解析，生知库 | 链接生命科学的每一步

Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

上皮间质转化引起的化疗耐药性是由异常的脂质代谢平衡造成的。

doi:10.7554/eLife.104374.

Atsushi Matsumoto #,Akihito Inoko #,Takuya Tanaka,Gen-Ichi Konishi,Waki Hosoda,Takahiro Kojima,Koji Ohnishi,Junichi Ikenouchi

代谢

发表日期：2026

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D-π-A Fluorophores with Strong Solvatochromism for Single-Molecule Ratiometric Thermometers

用于单分子比率温度计的具有强溶剂变色效应的D-π-A荧光团

期刊:Journal of the American Chemical Society

影响因子:15.6

doi:10.1021/jacs.5c01173

Hori, Alto; Matsumoto, Atsushi; Ikenouchi, Junichi; Konishi, Gen-Ichi

发表日期：2025

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A steady-state pool of calcium-dependent actin is maintained by Homer and controls epithelial mechanosensation.

Homer 维持着钙依赖性肌动蛋白的稳定池，并控制着上皮机械感觉。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2509784122

Matsuzawa Kenji, Suzuki Makoto, Cho Yuma, Fujinaga Ryoya, Ikenouchi Junichi

Mer

发表日期：2025

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Impact of 1 mm difference in interelectrode spacing on local electrograms and voltage/activation maps

电极间距相差 1 毫米对局部电图和电压/激活图的影响

期刊:Europace

影响因子:7.4

doi:10.1093/europace/euaf135

Yamaguchi, Junji; Takigawa, Masateru; Goya, Masahiko; Iwakawa, Hidehiro; Kawamura, Iwanari; Kato, Ryosuke; Honda, Masaki; Negishi, Miho; Tateishi, Ryo; Yamamoto, Tasuku; Ikenouchi, Takashi; Goto, Kentaro; Shigeta, Takatoshi; Nishimura, Takuro; Takamiya, Tomomasa; Tao, Susumu; Suzuki, Sayaka; Iwanaga, Takehiro; Miyazaki, Shinsuke; Sasano, Tetsuo

发表日期：2025

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Real-World Effectiveness and Safety of Mirikizumab Induction Therapy in Patients With Ulcerative Colitis: A Multicentre Retrospective Observational Study

米利珠单抗诱导治疗在溃疡性结肠炎患者中的真实世界疗效和安全性：一项多中心回顾性观察研究

期刊:Alimentary Pharmacology & Therapeutics

影响因子:6.7

doi:10.1111/apt.70140

Takagi, Yasuhiro; Sato, Toshiyuki; Nishiguchi, Takanori; Nogami, Akira; Igeta, Masataka; Yagi, Soichi; Ikenouchi, Maiko; Kawai, Mikio; Kamikozuru, Koji; Yokoyama, Yoko; Tomita, Toshihiko; Fukui, Hirokazu; Fukata, Masayuki; Kobayashi, Taku; Shinzaki, Shinichiro

Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

Rho-ROCK释放被隔离的claudin，促进快速新生紧密连接的形成。

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.102794

Yuma Cho ,Akari Taniguchi ,Akiharu Kubo ,Junichi Ikenouchi

ROCK

发表日期：2025

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Switching off hypertrophy: Conditional siRNA as a precision tool for heart failure therapy

关闭肥大：条件性siRNA作为心力衰竭治疗的精准工具

期刊:Molecular Therapy-Nucleic Acids

影响因子:6.1

doi:10.1016/j.omtn.2025.102760

Ikenouchi, Takashi; Cingolani, Eugenio

Effect of Chronic Social Defeat Stress on the Small-Intestinal Environment, Including the Gut Flora, Immune System, and Mucosal Barrier Integrity

慢性社会挫败应激对小肠环境（包括肠道菌群、免疫系统和黏膜屏障完整性）的影响

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26199359

Yagi, Soichi; Fukui, Hirokazu; Shiraishi, Tetsuya; Kaku, Koji; Wakita, Midori; Takagi, Yasuhiro; Ikenouchi, Maiko; Sato, Toshiyuki; Kawai, Mikio; Yokoyama, Yoko; Takagawa, Tetsuya; Tomita, Toshihiko; Kitaoka, Shiho; Shinzaki, Shinichiro

Propensity score-matched real-world comparative treatment outcomes of Janus kinase inhibitors for ulcerative colitis in patients with and without prior exposure to anti-tumor necrosis factor α antibody

倾向评分匹配的真实世界比较研究：Janus激酶抑制剂治疗溃疡性结肠炎患者（既往接受过抗肿瘤坏死因子α抗体治疗和未接受过抗肿瘤坏死因子α抗体治疗）的疗效

期刊:Intestinal Research

影响因子:3.9

doi:10.5217/ir.2024.00148

Ikenouchi, Maiko; Fukui, Hirokazu; Yagi, Soichi; Nogami, Akira; Kaku, Koji; Sato, Toshiyuki; Kawai, Mikio; Kamikozuru, Koji; Yokoyama, Yoko; Takagawa, Tetsuya; Tomita, Toshihiko; Kobayashi, Taku; Shinzaki, Shinichiro

CaMKII nucleates an osmotic protein supercomplex to induce cellular bleb expansion.

CaMKII 成核形成渗透蛋白超复合物，诱导细胞泡扩张。

Chemotherapy resistance due to epithelial-to-mesenchymal transition is caused by abnormal lipid metabolic balance

上皮间质转化引起的化疗耐药性是由异常的脂质代谢平衡造成的。

D-π-A Fluorophores with Strong Solvatochromism for Single-Molecule Ratiometric Thermometers

用于单分子比率温度计的具有强溶剂变色效应的D-π-A荧光团

A steady-state pool of calcium-dependent actin is maintained by Homer and controls epithelial mechanosensation.

Homer 维持着钙依赖性肌动蛋白的稳定池，并控制着上皮机械感觉。

Impact of 1 mm difference in interelectrode spacing on local electrograms and voltage/activation maps

电极间距相差 1 毫米对局部电图和电压/激活图的影响

Real-World Effectiveness and Safety of Mirikizumab Induction Therapy in Patients With Ulcerative Colitis: A Multicentre Retrospective Observational Study

米利珠单抗诱导治疗在溃疡性结肠炎患者中的真实世界疗效和安全性：一项多中心回顾性观察研究

Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

Rho-ROCK释放被隔离的claudin，促进快速新生紧密连接的形成。

Switching off hypertrophy: Conditional siRNA as a precision tool for heart failure therapy

关闭肥大：条件性siRNA作为心力衰竭治疗的精准工具

Effect of Chronic Social Defeat Stress on the Small-Intestinal Environment, Including the Gut Flora, Immune System, and Mucosal Barrier Integrity

慢性社会挫败应激对小肠环境（包括肠道菌群、免疫系统和黏膜屏障完整性）的影响

Propensity score-matched real-world comparative treatment outcomes of Janus kinase inhibitors for ulcerative colitis in patients with and without prior exposure to anti-tumor necrosis factor α antibody

倾向评分匹配的真实世界比较研究：Janus激酶抑制剂治疗溃疡性结肠炎患者（既往接受过抗肿瘤坏死因子α抗体治疗和未接受过抗肿瘤坏死因子α抗体治疗）的疗效