A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria
一项随机、双盲 II 期临床试验，旨在评估单剂量阿替芬诺和哌喹联合治疗对成人和儿童单纯性恶性疟疾的疗效、安全性、耐受性和药代动力学。
期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-017-0940-3
Macintyre, Fiona; Adoke, Yeka; Tiono, Alfred B; Duong, Tran Thanh; Mombo-Ngoma, Ghyslain; Bouyou-Akotet, Marielle; Tinto, Halidou; Bassat, Quique; Issifou, Saadou; Adamy, Marc; Demarest, Helen; Duparc, Stephan; Leroy, Didier; Laurijssens, Bart E; Biguenet, Sophie; Kibuuka, Afizi; Tshefu, Antoinette Kitoto; Smith, Melnick; Foster, Chanelle; Leipoldt, Illse; Kremsner, Peter G; Phuc, Bui Quang; Ouedraogo, Alphonse; Ramharter, Michael
