Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors.
羟氯喹可防止耐药性,并增强 SHP2 抑制剂对 NF1 相关恶性周围神经鞘瘤的抗肿瘤作用
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2407745121
Sait Sameer Farouk, Tang Kwan Ho, Angus Steven P, Brown Rebecca, Sun Daochun, Xie Xuanhua, Iltis Charlene, Lien Michelle, D Socci Nicholas, Bale Tejus A, Davis Christopher, Dixon Shelley A H, Zhang Chi, Wade Clapp D, Neel Benjamin G, Parada Luis F