日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Chemical genomics language model toward reliable and explainable compound-protein interaction exploration

化学基因组学语言模型，旨在探索可靠且可解释的化合物-蛋白质相互作用

期刊:Journal of Cheminformatics
影响因子:5.7
doi:10.1186/s13321-026-01155-z
Koyama, Takuto; Tsumura, Hayato; Okita, Ryunosuke; Yamazaki, Kimihiro; Hasegawa, Aki; Imamura, Keiko; Kato, Takashi; Iwata, Hiroaki; Kojima, Ryosuke; Inoue, Haruhisa; Matsumoto, Shigeyuki; Okuno, Yasushi
发表日期：2026
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Apolipoprotein E Deficiency Impairs Human Microglial Proliferation Accompanied by Elevated Cellular Oxidative Stress

载脂蛋白E缺乏会损害人类小胶质细胞增殖，并伴有细胞氧化应激升高

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.71074
Kim, Dayoung; Kondo, Takayuki; Imamura, Keiko; Tsukita, Kayoko; Nagahashi, Ayako; Sakasai, Tomoki; Inoue, Haruhisa
胶质细胞
氧化应激
Human
细胞生物学
毒理研究
发表日期：2026
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Phenotypic screening of human iPSC-derived neurons identifies thienopyridones as neuritogenic small molecules

对人诱导多能干细胞衍生神经元的表型筛选发现噻吩并吡啶酮类化合物是具有促神经突生长作用的小分子化合物。

期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2026.115529
Imamura, Keiko; Yukikate, Hiroshi; Hioki, Takeshi; Okusa, Aya; Shibata, Keisuke; Narvaiza, Iñigo; Kaieda, Akira; Saito, Bunnai; Sakai, Nozomu; Anh Suong, Dang Ngoc; Niki, Takeshi; Arioka, Yuko; Ozaki, Norio; Inoue, Haruhisa
细胞生物学
发育与干细胞
神经科学
干细胞
发表日期：2026
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Striosome Circuitry Stimulation Inhibits Striatal Dopamine Release and Locomotion.

纹状体回路刺激抑制纹状体多巴胺释放和运动

期刊:Journal of Neuroscience
影响因子:4
doi:10.1523/JNEUROSCI.0457-24.2024
Okunomiya Taro, Watanabe Dai, Banno Haruhiko, Kondo Takayuki, Imamura Keiko, Takahashi Ryosuke, Inoue Haruhisa
信号转导
发表日期：2025
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Phototoxicity avoidance is a potential therapeutic approach for retinal dystrophy caused by EYS dysfunction

避免光毒性是治疗由EYS功能障碍引起的视网膜营养不良的一种潜在治疗方法。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.174179
Otsuka, Yuki; Imamura, Keiko; Oishi, Akio; Asakawa, Kazuhide; Kondo, Takayuki; Nakai, Risako; Suga, Mika; Inoue, Ikuyo; Sagara, Yukako; Tsukita, Kayoko; Teranaka, Kaori; Nishimura, Yu; Watanabe, Akira; Umeyama, Kazuhiro; Okushima, Nanako; Mitani, Kohnosuke; Nagashima, Hiroshi; Kawakami, Koichi; Muguruma, Keiko; Tsujikawa, Akitaka; Inoue, Haruhisa
毒理研究
EYS
发表日期：2024
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Design of neural organoids engineered by mechanical forces

利用机械力设计神经类器官

期刊:IBRO Neuroscience Reports
影响因子:2.9
doi:10.1016/j.ibneur.2024.01.004
Suong, Dang Ngoc Anh; Imamura, Keiko; Kato, Yoshikazu; Inoue, Haruhisa
3D/类器官
发表日期：2024
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Protocol for a phase 2 study of bosutinib for amyotrophic lateral sclerosis using real-world data: induced pluripotent stem cell-based drug repurposing for amyotrophic lateral sclerosis medicine (iDReAM) study

利用真实世界数据开展博舒替尼治疗肌萎缩侧索硬化症的 II 期研究方案：基于诱导多能干细胞的肌萎缩侧索硬化症药物再利用 (iDReAM) 研究

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2023-082142
Imamura, Keiko; Izumi, Yuishin; Egawa, Naohiro; Ayaki, Takashi; Nagai, Makiko; Nishiyama, Kazutoshi; Watanabe, Yasuhiro; Murakami, Takenobu; Hanajima, Ritsuko; Kataoka, Hiroshi; Kiriyama, Takao; Nanaura, Hitoki; Sugie, Kazuma; Hirayama, Takehisa; Kano, Osamu; Nakamori, Masahiro; Maruyama, Hirofumi; Haji, Shotaro; Fujita, Koji; Atsuta, Naoki; Tatebe, Harutsugu; Tokuda, Takahiko; Takahashi, Naoto; Morinaga, Akiko; Tabuchi, Riko; Oe, Motoki; Kobayashi, Mihoko; Lobello, Kasia; Morita, Satoshi; Sobue, Gen; Takahashi, Ryosuke; Inoue, Haruhisa
细胞生物学
发育与干细胞
干细胞
发表日期：2024
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Safety and tolerability of bosutinib in patients with amyotrophic lateral sclerosis (iDReAM study): A multicentre, open-label, dose-escalation phase 1 trial

博舒替尼治疗肌萎缩侧索硬化症患者的安全性和耐受性（iDReAM 研究）：一项多中心、开放标签、剂量递增的 1 期试验

期刊:EClinicalMedicine
影响因子:10
doi:10.1016/j.eclinm.2022.101707
Imamura, Keiko; Izumi, Yuishin; Nagai, Makiko; Nishiyama, Kazutoshi; Watanabe, Yasuhiro; Hanajima, Ritsuko; Egawa, Naohiro; Ayaki, Takashi; Oki, Ryosuke; Fujita, Koji; Uozumi, Ryuji; Morinaga, Akiko; Hirohashi, Tomoko; Fujii, Yosuke; Yamamoto, Takuya; Tatebe, Harutsugu; Tokuda, Takahiko; Takahashi, Naoto; Morita, Satoshi; Takahashi, Ryosuke; Inoue, Haruhisa
发表日期：2022
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A Comparison of the Contents of Disaster Nursing Practices and Perceived Difficulties among Nurses Working at Welfare Evacuation Shelters during Natural Disasters and Multiple Disasters: A Qualitative Study

自然灾害和多重灾害期间，在福利避难所工作的护士的灾害护理实践内容及感知困难的比较：一项定性研究

期刊:International Journal of Environmental Research and Public Health
影响因子:
doi:10.3390/ijerph192416610
Shiomitsu, Yoshiko; Yamaguchi, Takumi; Imamura, Keiko; Koyama, Tamami; Tsuchihashi, Hitomi; Kawaoka, Yuta; Matsunari, Yuko
发表日期：2022
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Prediction of Compound Bioactivities Using Heat-Diffusion Equation.

利用热扩散方程预测化合物生物活性

期刊:Patterns
影响因子:7.4
doi:10.1016/j.patter.2020.100140
Hidaka Tadashi, Imamura Keiko, Hioki Takeshi, Takagi Terufumi, Giga Yoshikazu, Giga Mi-Ho, Nishimura Yoshiteru, Kawahara Yoshinobu, Hayashi Satoru, Niki Takeshi, Fushimi Makoto, Inoue Haruhisa
其它
发表日期：2020
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