日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Boosting SIV-specific CD8+ T cell responses prior to ART interruption extends time to SIVmac239 rebound.

在 ART 中断之前增强 SIV 特异性 CD8+ T 细胞反应可延长 SIVmac239 反弹的时间。

Omange Were R, Varco-Merth Benjamin D, Fadeyi Omo, Marenco Alejandra, Takata Hiroshi, Duell Derick M, Goodwin William D, Armitage Paula, Fennessey Christine M, Kose Emek, Immonen Taina T, Kosmider Ewelina, Bosche William J, Fast Randy, Homick Chris, Oswald Kelli, Shoemaker Rebecca, Bochart Rachele, MacAllister Rhonda, Labriola Caralyn S, Smedley Jeremy V, Axthelm Michael K, Edlefsen Paul T, Keele Brandon F, Lifson Jeffrey D, Gergen Janina, Petsch Benjamin, Rauch Susanne, Picker Louis J, Okoye Afam A

Dissecting the steps in early simian immunodeficiency virus dissemination following mucosal and intravenous infection of rhesus macaques

剖析恒河猴黏膜和静脉感染后早期猴免疫缺陷病毒传播的步骤

Docken, Steffen S; Macairan, Agatha; Schlub, Timothy E; Fennessey, Christine M; Varco-Merth, Benjamin; Picker, Louis J; Okoye, Afam A; Immonen, Taina T; Cromer, Deborah; Keele, Brandon F; Davenport, Miles P

Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy.

腺相关病毒递送 Env 特异性抗体可防止停止抗逆转录病毒治疗后 SIV 反弹

Klenchin Vadim A, Clark Natasha M, Keles Nida K, Capuano Saverio 3rd, Mason Rosemarie, Gao Guangping, Broman Aimee, Kose Emek, Immonen Taina T, Fennessey Christine M, Keele Brandon F, Lifson Jeffrey D, Roederer Mario, Gardner Matthew R, Evans David T

Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression

对恒河猴T细胞受体恒定区的修饰可改善T细胞受体的细胞表面表达。

Coren, Lori V; Trivett, Matthew T; Welker, Jorden L; Thomas, James A; Gorelick, Robert J; Kose, Emek; Immonen, Taina T; Czarra, Kelli; Fennessey, Christine M; Trubey, Charles M; Lifson, Jeffrey D; Swanstrom, Adrienne E

BCL-2 Inhibition via Venetoclax at ART Initiation Induces Long-Term Reduction of the Intact SIV Reservoir.

在抗逆转录病毒治疗开始时通过维奈托克抑制BCL-2可长期减少完整的SIV病毒库

Salinas Tomas Raul Wiche, Harper Justin, Deleage Claire, Nguyen Kevin, Auger James, Flores Hannah R, Wilkes Amelia C, Stammen Rachelle L, Wood Jennifer S, Tharp Gregory K, Bosinger Steven E, Cottrell Mackenzie L, Kose Emek, Immonen Taina T, Lifson Jeffrey D, Laird Gregory M, Keele Brandon F, Jones R Brad, Badley Andrew D, Silvestri Guido, Kulpa Deanna A, Paiardini Mirko

No evidence for ongoing replication on ART in SIV-infected macaques

没有证据表明SIV感染的猕猴在接受抗逆转录病毒治疗期间病毒仍在持续复制。

Immonen, Taina T; Fennessey, Christine M; Lipkey, Leslie; Newman, Laura; Macairan, Agatha; Bosche, Marjorie; Waltz, Nora; Del Prete, Gregory Q; Lifson, Jeffrey D; Keele, Brandon F

Genetically barcoded SIV reveals the emergence of escape mutations in multiple viral lineages during immune escape.

通过基因条形码标记的SIV揭示了免疫逃逸过程中多个病毒谱系中逃逸突变的出现

Immonen Taina T, Camus Celine, Reid Carolyn, Fennessey Christine M, Del Prete Gregory Q, Davenport Miles P, Lifson Jeffrey D, Keele Brandon F

Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo

体内HIV-1和SIV逆转录的低水平替代tRNA引物

Fennessey, Christine M; Camus, Celine; Immonen, Taina T; Reid, Carolyn; Maldarelli, Frank; Lifson, Jeffrey D; Keele, Brandon F

Reduced evolutionary rates in HIV-1 reveal extensive latency periods among replicating lineages

HIV-1进化速率降低揭示了复制谱系之间存在较长的潜伏期

Immonen, Taina T; Leitner, Thomas